Encourages independent and critical thought.
This comment is not public.
Kazi Islam, Ph.D., serves as Associate Professor of Health in the John W. Garland College of Engineering, Science, Technology, and Agriculture at Central State University, a position he has held since August 2019. He earned his Ph.D. in Physiology, with a focus on Biochemistry and Molecular Biology, from Osaka University Medical School in Osaka, Japan, in 1996. His postdoctoral research at UT Southwestern Medical Center in Dallas, Texas, centered on heart disease, encompassing both clinical and basic science investigations. There, he explored the hypothesis that alpha-tocopherol, an antioxidant, inhibits monocyte-endothelial cell adhesion by preventing activation of the nuclear transcription factor kappa B (NF-κB). Prior to Central State University, he was affiliated with the Department of Pharmacology and Experimental Therapeutics at Louisiana State University Health Sciences Center in New Orleans.
Dr. Islam's research investigates gene transcription and regulation in disease states, with a primary emphasis on heart disease, the leading cause of morbidity and mortality in the United States. His current work elucidates the molecular mechanisms by which gasotransmitters nitric oxide (NO) and hydrogen sulfide (H2S) contribute to the prevention and protection against cardiovascular diseases and diabetes. Notable publications include "Diabetes Mellitus and Associated Vascular Disease: Pathogenesis, Complications, and Evolving Treatments" (2025), "Roles of Hydrogen Sulfide (H2S) as a Potential Therapeutic Agent in Cardiovascular Diseases: A Narrative Review" (2024), "H2S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins" (2023), "Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure" (2016), and "Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability" (2016). He has contributed to university initiatives, including presentations on diabetes and cardiovascular diseases at Central State University Extension's Urban and Small-Scale Farm Conference (2025) and Diabetes Awareness Day (2024).
