A major focus of the laboratory is obesity-associated endometrial cancer. As obesity rates continue to rise, understanding the molecular mechanisms linking obesity to endometrial carcinogenesis has become increasingly important. Current projects investigate the role of Rab27a-mediated EV secretion and PIAS3 signaling in the initiation and progression of endometrial cancer, with the goal of developing early detection biomarkers and targeted therapeutic strategies.
Candidate Qualifications
We seek highly motivated candidates with a PhD in Biomedical Sciences, OB/GYN, Cancer Biology, or a related field. Prior experience in gynecologic oncology and molecular biology is preferred.
Experience in the following areas is desirable:
- Cell and tissue culture
- Exosome/EV isolation and characterization
- Molecular and biochemical techniques (RT-qPCR, Western blotting, ELISA, IHC, gene transfection)
- In vivo mouse models, particularly obesity-associated endometrial cancer models
- Transcriptional and post-transcriptional regulatory mechanisms
Preference will be given to applicants with expertise in EV biology, EV-mediated signaling, and early-stage ovarian or endometrial cancer development.
Experience Requirements
Doctoral degree (PhD) in Biomedical Sciences, Cancer Biology, or related discipline. One to two years of research experience in cancer biology or a closely related field. Demonstrated ability to conduct productive, independent research, as evidenced by peer-reviewed publications, conference presentations, and contributions to innovative experimental approaches or translational research programs.
Additional Information
Location: Tzagournis Medical Research Facility (0163)
Position Type: Term (Fixed Term)
Scheduled Hours: 40
Shift: First Shift
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
