synthetic chromosomes. We have recently contributed to the design, build and test of the first non-native eukaryotic chromosome, called a neoChromosome. This PhD project builds upon this work to clarify and test the design principles for stable maintenance of fully synthetic chromosomes within eukaryotic cells.

We offer a highly collaborative multi-disciplinary PhD between the Nieduszynski (chromosome biology; technology development) and Grandellis (engineering biology; molecular biology automation) groups. The student will work in a rapidly developing field and gain a unique expertise in engineering biology, technology development and automation - skills that are in high demand for modern biological research in both academia and industry. The project will be conducted at the Earlham Institute, a BBSRC-supported, world-class research centre for bioinformatics and genome biology.

synthetic chromosomes. We have recently contributed to the design, build and test of the first non-native eukaryotic chromosome, called a neoChromosome. This PhD project builds upon this work to clarify and test the design principles for stable maintenance of fully synthetic chromosomes within eukaryotic cells.

We offer a highly collaborative multi-disciplinary PhD between the Nieduszynski (chromosome biology; technology development) and Grandellis (engineering biology; molecular biology automation) groups. The student will work in a rapidly developing field and gain a unique expertise in engineering biology, technology development and automation - skills that are in high demand for modern biological research in both academia and industry. The project will be conducted at the Earlham Institute, a BBSRC-supported, world-class research centre for bioinformatics and genome biology.