Sebastian Amos

Dr. Sebastian Amos serves as Lecturer and Anatomy Discipline Lead in the MD Education Unit of the UWA Medical School at the University of Western Australia. Having completed his PhD in Cancer Mechanobiology and Bioimage Informatics at UWA, where he served as a Hackett Postgraduate Research Scholar in the School of Human Sciences and investigated the role of cellular adhesion in tumour growth and cancer metastasis, Amos has taught anatomy since 2017 in undergraduate and postgraduate units. He utilizes his skills in programming and image science to develop 3D digital and printed anatomical teaching resources, contributing to an international collaboration that characterized the adherent-to-suspension transition in cancer cell dissemination.

Amos's research specializes in bioimage analysis and informatics for 2D and 3D cell biology, quantitative image analysis for histopathology, and segmentation and quantification of medical imaging datasets. He created the Fluorescent Object and Cell gpU-accelerated Segmentation Toolbox (FOCUST), a freely available plugin for the FIJI distribution of ImageJ, and has collaborated on projects in stem cell, cardiac, neuronal/glial, airway mechanobiology, drug delivery, preterm birth, tumour-immune biology, and novel optical and mechanical imaging techniques. Key publications include "FOCUST: Fluorescent Object and Cell gpU-Accelerated Segmentation Toolbox" (Small Methods, 2025), "Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination" (Molecular Cancer, 2023), "Antenatal creatine supplementation reduces persistent fetal lung inflammation and oxidative stress in an ovine model of chorioamnionitis" (American Journal of Physiology - Lung Cellular and Molecular Physiology, 2024), "In situ stress estimation in quantitative micro-elastography" (Biomedical Optics Express, 2024), and "Multimodal mechano-microscopy reveals mechanical phenotypes of breast cancer spheroids in three dimensions" (APL Bioengineering, 2024). His teaching excellence is evidenced by awards such as the 2025 UWA Award for Excellence and Innovation in Learning and Teaching: Digital Transformation, UWA Medical School Excellence in Teaching (2023, 2024, 2025), and Western Australian Medical Students' Society Preclinical Tutor of the Year (2025).

Professional Email: sebastian.amos@uwa.edu.au