Rate My Professor Jose Sanchez-Alonso

Jose Sanchez-Alonso is a Research Fellow at the National Heart and Lung Institute within the Faculty of Medicine at Imperial College London. He serves as Deputy Director of the Cellular Mechanosensing and Functional Microscopy Centre. An electrophysiologist with 18 years of experience, his research interests include heart failure, cardiac function, electrophysiology, cell culture, cardiomyopathies, patch-clamp electrophysiology, patch clamp recording, cell signaling, in vitro electrophysiology, and neuron culture.

Affiliated with the Julia Gorelik laboratory at the National Heart and Lung Institute, he has authored 52 publications with 1,094 citations. Key publications include: "Microtubule-Mediated Regulation of β₂ AR Translation and Function in Failing Hearts" (2023), "Functional LTCC-β₂AR Complex Needs Caveolin-3 and Is Disrupted in Heart Failure" (2023), "CASK silencing favors systolic function by regulating junction's signaling" (2023), "Investigating the functional communication between sympathetic neurons and HiPSC-CMs in vitro" (2022), "GPER limits adverse changes to Ca signalling and arrhythmogenic activity in ovariectomised guinea pig cardiomyocytes" (2022), "Intrinsic cell rheology drives junction maturation" (2022), "Nerve growth factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro‐cardiac junction" (2022), "Local hyperactivation of L-type Ca channels increases spontaneous Ca release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats" (2021), "Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes" (2021), "Nanoscale Study of Calcium Handling Remodeling in Right Ventricular Cardiomyocytes Following Pulmonary Hypertension" (2020), "Ankyrin-G mediates targeting of both Na⁺ and KATP channels to the rat cardiac intercalated disc" (2020), "β₃-Adrenoceptor redistribution impairs NO/cGMP/PDE₂ signalling in failing cardiomyocytes" (2020), "Microtubules regulate cardiomyocyte transversal Young’s modulus" (2020), "The adhesion function of the sodium channel beta subunit (β₁) contributes to cardiac action potential propagation" (2018), and "Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure" (2016).