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Dr. Amit Awasthi is a Senior Professor at the Translational Health Science and Technology Institute (THSTI), specializing in immunology. He obtained his M.Sc. in Biotechnology from Jiwaji University, Gwalior, and Ph.D. in Immunology from the National Center for Cell Science, Pune. Awasthi completed postdoctoral training at Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, where he also served as Instructor (Junior Faculty) at Harvard Medical School. He joined THSTI in 2012 as a Senior Professor, leading research in the Centre for Immunobiology and Immunotherapy and the Immunology Core Laboratory.
His research investigates the interplay between effector and regulatory T cells in inflammatory bowel disease and gut infections, T cell differentiation pathways in immunity, autoimmunity, and cancer immunity, metabolic regulation of T cells, checkpoint inhibitors in cancer, and transcriptional regulation of Th9 and Th17 cells. Awasthi has published extensively in high-impact journals, with key papers including 'Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses' (Nature Medicine, 2004), 'IL-21 initiates an alternate pathway to induce proinflammatory Th17 cells' (Nature, 2007), 'A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells' (Nature Immunology, 2007), and 'IL-4 inhibits TGF-β-induced Foxp3+ T cells and generates a Foxp3- IL-10/IL-9 T cell population' (Nature Immunology, 2008). His scholarly output exceeds 16,000 citations. Notable awards include Junior and Senior Research Fellowships from the Department of Biotechnology and Council of Scientific & Industrial Research (2001-2003), G.P. Talwar Young Scientist Award (2004), Ramalingaswami Fellowship (2011), Innovative Young Biotechnologist Award (2011), DBT-Wellcome India Alliance Intermediate Fellowship (2012), GN Ramachandran National Bioscience Award (2021), Fellow of the Indian National Science Academy (2025), National Academy of Sciences, India, and Sun Pharma Science Foundation award. He served as Secretary of the Indian Immunology Society and his team is recognized as an ICMR-Collaborating Centre of Excellence.