Rate My Professor Youssef Idaghdour

Idaghdour's research examines the interplay of genetic and environmental factors in health-related phenotypes, disease susceptibility, and outcomes across biological scales from genome architecture to epigenetic regulation and protein function. His lab generates high-dimensional genomic data from single cells, tissues, and populations to investigate metabolic traits, immune responses to cancer and infections including malaria and COVID-19, host-pathogen interactions, and gene-environment effects. He also develops genetic tools for ecological genomics and population studies of endangered wildlife and marine species such as Houbara bustards and falcons. Key publications include 'Recombination affects accumulation of damaging and disease-associated mutations in human populations' in Nature Genetics (2015), 'High-resolution genomic analysis of human mitochondrial RNA sequence variation' in Science (2014), 'Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria' in Nature Communications (2020), and 'Metabolome modulation of the host adaptive immunity in human malaria' in Nature Metabolism (2021). Idaghdour has received the Fulbright Scholarship, Banting Postdoctoral Fellowship, and a 2021 Chan Zuckerberg Initiative grant of approximately USD 2.7 million to build an African Ancestry Immune Cell Atlas promoting global representation in single-cell genomics.