Rate My Professor Torsten Kleffmann

Dr. Torsten Kleffmann is a Senior Research Fellow and Operations Manager at the Centre for Protein Research (CPR), Research Infrastructure Centre, in the Department of Biochemistry, School of Biomedical Sciences, Division of Health Sciences, Faculty of Biomedical Sciences at the University of Otago. He holds an MSc and PhD. Kleffmann's research interests center on mass spectrometry-based proteomics and protein analysis, with emphasis on method establishment and development in mass spectrometry-based proteome and protein research across various biological systems. In his role as Operations Manager, he manages the CPR, providing advanced proteomic services and supporting collaborative projects in diverse fields including immunology, bioarchaeology, enzymology, and reproductive biology.

Kleffmann has an extensive record of peer-reviewed publications reflecting the impact of his proteomic expertise. Recent key works include: King, C. L. et al. (2025), 'Osteological sex estimation versus proteomic sex "determination": What effect do our techniques have on the way we view the people of the past?', American Journal of Biological Anthropology; Broomfield, G. R. et al. (2025), 'Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position', FEBS Letters; Reddington, C. J. et al. (2025), 'Unconventional structure and function of PHD domains from additional sex combs-like proteins', The FEBS Journal; Willis, A. et al. (2025), 'Living in the middle of the edge: An insight into ancient subsistence practices in Myanmar', Archaeological & Anthropological Sciences; Kumar, A. et al. (2025), 'Quantitative Proteomics on Immune Cells of ME/CFS Patients Using SWATH-MS', Methods in Molecular Biology. Further contributions encompass Peppercorn, K. et al. (2023), 'A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic fatigue syndrome', Scientific Reports; Winterbourn, C. C. et al. (2023), 'Carbon dioxide/bicarbonate is required for sensitive detection of hydrogen peroxide by boronate probes', Proceedings of the National Academy of Sciences; Nair, S. S. et al. (2024), 'Comparative lipidomics profiles of planktonic and biofilms of the ESKAPE pathogen Acinetobacter baumannii', Analytical Chemistry; Johnson, S. L. et al. (2020), 'Ovarian fluid proteome variation associates with sperm swimming speed in an externally fertilizing fish', Proceedings of the Royal Society B; Templeton, E. M. et al. (2023), 'Comparison of SPEED, S-Trap, and In-Solution-Based Proteomic Sample Preparation Workflows', Journal of Proteome Research. These publications highlight his role in advancing proteomic methodologies and applications.