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5.04/30/2025

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About Suming

Suming Huang, PhD, MS, is Professor of Pediatrics and Pharmacology and Chair of the Four Diamonds Epigenetics and Gene Regulation Research Program in Pediatric Oncology in the Department of Pediatrics at Pennsylvania State University College of Medicine. Prior to his current roles, he was affiliated with the University of Florida. Dr. Huang's research specializations include epigenetic mechanisms governing gene expression in hematopoiesis and leukemia development. His laboratory investigates the roles of long noncoding RNAs (lncRNAs), such as HoxBlinc and HOTTIP, in reprogramming chromatin architecture, including topologically associating domains (TADs) independent of CTCF, to activate HOX gene clusters in leukemia. These studies elucidate how epigenetic dysregulation contributes to oncogenesis and stem cell maintenance in acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia (T-ALL).

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