
University of Western Australia
Brings enthusiasm and expertise to class.
Inspires confidence and independent thinking.
Encourages students to think independently.
Encourages deep understanding and curiosity.
Encourages creative and innovative thinking.
Yu Suk Choi is an Associate Professor in the School of Human Sciences at the University of Western Australia, where he leads the Cell Mechanobiology Lab. He completed his PhD in Stem Cell and Tissue Engineering at the University of Melbourne in 2010, with a thesis titled 'Engineering Cardiac Tissue from Human Adult Stem Cells'. Subsequently, he served as a Postdoctoral Scholar in Bioengineering at the University of California, San Diego, and the Sanford Consortium for Regenerative Medicine from April 2010 to June 2013. He then held a Research Fellow position in Cardiology at the University of Sydney's Kolling Institute from July 2013 to June 2015. Choi joined the University of Western Australia in 2015 as a lecturer in the School of Anatomy, Physiology and Human Biology (now School of Human Sciences) and progressed to Associate Professor.
Choi's research focuses on stem cell mechanotransduction, examining how extracellular matrix mechanical cues like stiffness control stem cell differentiation, migration, and proliferation for tissue engineering and regenerative medicine. His work also addresses cancer mechanobiology, developing 3D biomaterials to model tumor microenvironments and metastasis. Key publications include 'Interplay of matrix stiffness and protein tethering in stem cell differentiation' in Nature Materials (2014), 'Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels' in Proceedings of the National Academy of Sciences (2017), 'Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength' in Biotechnology Journal (2013), and 'Volume adaptation controls stem cell mechanotransduction' in ACS Applied Materials & Interfaces (2019). With 92 research outputs and highly cited papers exceeding 1000 citations each, his contributions influence mechanobiology and regenerative medicine. Awards include the Bob Fraser New Investigator Award (2016), School of Human Sciences Mid-Career Research Award (2023), Barbara Ell Seminar Series Lecturer (2017), and Heart Foundation Future Leader Fellowship (101173). He has received NHMRC funding for projects such as nuclear mechanobiology in migration and metastasis.
Professional Email: yusuk.choi@uwa.edu.au