Rate My Professor Subree Subramanian

Subree Subramanian, MS, PhD, is a Professor in the Department of Surgery at the University of Minnesota Medical School, specializing in Basic and Translational Research within the field of Medicine. He earned his PhD in Molecular and Cellular Biology from the Centre for Cellular and Molecular Biology, Jawaharlal Nehru University, India, in 2003, along with a Postgraduate Diploma in Patents Law from the National Academy of Legal Studies & Research that same year. He holds an MS in Biotechnology and a BS in Agricultural Sciences, both from Tamil Nadu Agricultural University, India, in 1998 and 1995, respectively. Following a postdoctoral fellowship in the Department of Pathology at Stanford University from 2003 to 2007, Subramanian joined the University of Minnesota in 2007 as an Assistant Professor in the Department of Laboratory Medicine and Pathology. He advanced to Assistant Professor in the Department of Surgery in 2010, became a tenured Associate Professor in 2015, and was promoted to full Professor in 2022. He also serves as Chief Scientific Officer of EV Therapeutics Inc. since 2020, Director of the Resident Research Enrichment Program in the Department of Surgery, and Co-leader of the Gastrointestinal Cancer Translational Working Group at the Masonic Cancer Center. Subramanian is a Senior Graduate Faculty member in the Microbiology, Immunology and Cancer Biology (MICaB), Molecular Pharmacology and Therapeutics (MPaT), and Bioinformatics and Computational Biology (BICB) PhD programs.

Subramanian's research program elucidates molecular mechanisms of immune evasion in cancers, particularly colorectal cancer and osteosarcoma, focusing on tumor-derived extracellular vesicles, gut microbiome interactions, and atypical chemokine receptor 4 (ACKR4) in anti-tumor immunity. His lab has identified how cancer cells and the microbiome suppress immune responses, including T-cell costimulation via exosomes, with implications for immunotherapy. He has authored over 120 peer-reviewed articles, including key publications such as 'Tumor-derived extracellular vesicles in the colorectal cancer immune environment and immunotherapy' (Pharmacology & Therapeutics, 2023), 'Cancer Immunology and Immunotherapies: Mechanisms that affect antitumor immune response and treatment resistance' (Cancers, 2021), and 'Tumor-secreted extracellular vesicles regulate T-cell costimulation and can be manipulated to induce tumor-specific T-cell responses' (Gastroenterology, 2021). His work has garnered an h-index of 54, over 10,500 citations, and an i10-index of 124. Notable awards include the American Cancer Society Research Scholar Award (2013), University of Minnesota Frontiers in Biomedical Research Scholar Award (2013), and Masonic Scholar from the Masonic Cancer Center (2010). He serves as Section Editor-in-Chief for Vaccines and Associate Section Editor-in-Chief for Cancers, and holds memberships in the American Association for Cancer Research, American Association for Immunologists, Society for Immunotherapy of Cancer, and International Society for Extracellular Vesicles.