Rate My Professor Stephen Doughty

Professor Doughty’s research focuses on molecular modelling of G-protein coupled receptors (GPCRs) and membrane-bound receptors, as well as computer-aided drug design. He has supervised postgraduate projects in these areas and produced nine peer-reviewed research outputs spanning 1997 to 2018. Key publications include: “Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment” (2018, Journal of Molecular Graphics and Modelling, with Loo, J. S. E. et al.); “Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and α1 receptor antagonists” (2018, MedChemComm, with Heng, H. L. et al.); “Homology modeling of the human 5-HT1A, 5-HT2A, D1, and D2 receptors: Model refinement with molecular dynamics simulations and Docking evaluation” (2012, Journal of Molecular Modeling, with Yap, B. K. et al.); “Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme” (2007, Acta Crystallographica Section F, with AbuKhader, M. M. et al.); and “Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles” (2007, FEBS Journal, with Banks, E. C. et al.). His contributions advance computational approaches to pharmacology and support regional healthcare innovation.