Rate My Professor Samantha Lodge

Samantha Lodge is a Senior Lecturer in Nuclear Magnetic Resonance at Murdoch University, where she heads the Magnetic Resonance Laboratory at the Australian National Phenome Centre within the Health Futures Institute and Centre for Computational and Systems Medicine. Prior to her appointment at Murdoch, she contributed to the inaugural Phenome Centre at Imperial College London. Lodge holds a Doctor of Philosophy and has established herself as a leading researcher in biomolecular NMR spectroscopy and metabolomics applied to human health.

Her academic interests focus on high-throughput NMR-based metabolic phenotyping to uncover biomarkers for complex diseases. Key research includes stratification of sepsis patients in intensive care using differential plasma metabolic phenotypes, identifying 15 parameters such as neopterin, HDL cholesterol, and phospholipids for rapid one-hour diagnosis distinguishing non-sepsis, sepsis, and septic shock. She has advanced understanding of SARS-CoV-2 infection through studies on lipoprotein disruptions, incomplete recovery in post-acute COVID-19, and diffusion-edited NMR signatures. Additional contributions cover lipoprotein subclass variations by age, sex, and adiposity; metabolic phenotyping of burn injuries; post-COVID multisystem inflammatory syndrome in children; and xenobiotic toxicity atlases. Lodge has authored or co-authored over 60 peer-reviewed publications, including 'Stratification of Sepsis Patients on Admission into the Intensive Care Unit According to Differential Plasma Metabolic Phenotypes' (2024, Journal of Proteome Research); 'NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites' (2021, Journal of Proteome Research); 'Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial' (2018, Analytical Chemistry); 'Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection' (2020, Journal of Proteome Research); and 'Influences of Age, Sex and Adiposity on NMR-Derived Lipoprotein Profiles' (2025, PLOS One). With over 1,300 citations, her work influences precision medicine and diagnostic development. She supervises doctoral students and serves as guest editor for Metabolites special issue on metabolic signatures in human health and disease.