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Dr. Ross Graham serves as a Senior Lecturer in Molecular Genetics within the School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, at Curtin University. He is affiliated with Curtin Medical School and contributes to research initiatives in vascular and metabolic disorders through Curtin MRI. Graham holds a BSc (Hons) and PhD, complemented by professional designations MSB and CBiol, recognizing his membership in the Society of Biology and status as a Chartered Biologist. His academic career at Curtin University encompasses teaching and supervision in biomedical sciences, including PhD students such as Bryce Tremethick and Keea Inder-Smith, whose projects on iron-related diseases have secured scholarships.
Graham's research centers on iron homeostasis in the liver and its intersections with metabolic pathways, including lipid and glucose metabolism. He investigates the pathological mechanisms in non-alcoholic fatty liver disease, the liver complication of obesity, and hereditary haemochromatosis, the prevalent genetic disorder causing iron overload. His work employs molecular genetics approaches to elucidate iron dysregulation in these conditions. Key publications include 'Disruption of both Hfe and Tfr2 causes iron-induced liver injury' (2010, Hepatology), 'Statins Do Not Directly Inhibit the Activity of Major Epigenetic Enzymes' (2019, Cancers), 'Tracking biochemical changes induced by iron loading in primary hepatocytes using infrared microspectroscopy' (2021, Biochemical Journal), and 'Iron metabolism mediates the relationship between Vitamin C and non-alcoholic fatty liver disease: A Mendelian randomization study' (2022, Frontiers in Nutrition). Graham maintains memberships in the Australian Society for Medical Research and participates in collaborative projects, such as copper-binding drugs for mesothelioma therapy and synchrotron-based studies on iron in tissues. His contributions advance understanding of metabolic diseases through genetic and biochemical analyses.
