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Matthew Torres is an Associate Professor in the School of Biological Sciences at the Georgia Institute of Technology. He earned a B.S. in Biology from Humboldt State University in 1997 and a Ph.D. in Biochemistry and Biophysics from the University of North Carolina at Chapel Hill in 2007, where he also completed postdoctoral training until 2012. Earlier, he served as a Research Associate at Gene Logic Inc. from 1997 to 2001. Torres joined Georgia Tech as an Assistant Professor in 2012, promoted to Associate Professor in 2018. He is co-director of the Systems Mass Spectrometry Core Facility since 2015, founder and leader of the Molecular BioMedical Research Community since 2021, a member of the executive committee for the American Society for Pharmacology and Experimental Therapeutics since 2022, and on the editorial board of the Journal of Biological Chemistry since 2023. He has been recognized with the ASPET Molecular Pharmacology Division Early Career Award in 2022, the NIH Pathway to Independence Award (K99/R00) from 2010 to 2016, the Georgia Tech CTL/BP Junior Faculty Teaching Excellence Award in 2018, and the IBB Above and Beyond Award in 2016.
Torres's research centers on protein post-translational modifications, integrating quantitative proteomics, bioinformatics, cell biology, and biochemistry to investigate their regulation of G proteins and protein-protein interaction networks via phosphorylation, ubiquitination, and acetylation. His lab employs mass spectrometry, yeast genetics, dose-response assays, in vitro biochemistry, and microscopy to explore coordinated PTM regulation of signaling complexes, cross-pathway PTM coordination, PTM networks in stress adaptation, and PTM detection technologies. Key publications include "Generative β-hairpin design using a residue-based physicochemical property landscape" (Biophys. J., 2024), "Depletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins in the Human Proteome" (Metallomics, 2023), "N-terminal intrinsic disorder is an ancestral feature of Gγ subunits that influences the balance between different Gβγ signaling axes in yeast" (J. Biol. Chem., 2023), "Sod1 integrates oxygen availability to redox regulate NADPH production and the thiol redoxome" (Proc. Natl. Acad. Sci. U.S.A., 2022), and "Combinatorial phosphorylation modulates the structure and function of the G protein γ subunit in yeast" (Sci. Signal., 2021). Torres has mentored eight Ph.D. students (six graduated), eight postdocs, twelve M.S. students, ten undergraduates, and four high school students, teaching a course on Proteomics: Technologies and Applications.
