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Dr. Matthew Ross is a Professor in the Department of Comparative Biomedical Sciences at the College of Veterinary Medicine, Mississippi State University, where he also serves in the Center for Environmental Health Sciences. His discipline is Pharmacology and Toxicology. He earned a B.S. in Chemistry from the University of California at Berkeley in 1989. From July 1989 to August 1992, he worked as a Research Chemist and Group Leader in the Plant/Soil Metabolism Group at PTRL. He joined Mississippi State University as Professor in August 2019. Earlier in his career at the university, he was an Associate Professor of Molecular Toxicology in the Department of Basic Sciences, College of Veterinary Medicine, as noted in 2015. Ross has contributed to significant research initiatives, including serving as a co-investigator on a $3.3 million NIH grant awarded to the College of Veterinary Medicine in 2021 for chemical exposure studies. His laboratory has mentored numerous undergraduate and graduate students, several of whom have received prestigious awards such as Astronaut Scholarships, Goldwater Scholarships, and placements in undergraduate research symposia.
Ross's research focuses on molecular toxicology, including carboxylesterase activity, lipid peroxidation products, endocannabinoid metabolism, inflammation regulation, and the impacts of environmental xenobiotics and pesticides. Key publications include 'Inhibition of carboxylesterase activity of THP1 monocytes by reactive oxygen species' (2010), 'Catabolism of 4-Hydroxy-2-trans-Nonenal by THP1 Monocytes' (2011), 'Effects of Toxicologically Relevant Xenobiotics and the Lipid Peroxidation Product 4-Hydroxynonenal on the Expression and Activity of Carboxylesterases 1 and 2' (2014), 'Lipopolysaccharide suppresses carboxylesterase 2g activity and 2-arachidonoylglycerol hydrolysis: a possible mechanism to regulate inflammation' (2015), 'Error-prone PCR-based mutagenesis strategy for rapidly generating male-specific lethal influenza virus' (2015), and 'Pharmacokinetics of three novel pyridinium aldoxime carbamates in rat plasma' (2022). He has received the Donald Zacharias Early Career Undergraduate Research Mentor Award, a 2019 Research Award from the Office of Research and Economic Development, and a 2025 Safety Challenge Coin for lab safety. Ross has been recognized for excellence in undergraduate mentoring and research support. His work advances understanding of toxicological mechanisms in environmental health and veterinary medicine.
