Rate My Professor Kristofer Fritz

Kristofer Fritz, PhD, is an Associate Professor in the Department of Pharmaceutical Sciences at the Skaggs School of Pharmacy, University of Colorado Anschutz Medical Campus. He holds a concurrent faculty appointment in the School of Medicine, Division of Cardiology. Fritz earned a Bachelor of Science in Biochemistry from La Sierra University in Riverside, California, a Doctor of Philosophy in Biochemistry from Loma Linda University in Loma Linda, California, and completed a postdoctoral fellowship at the University of Colorado.

Fritz's research elucidates biochemical mechanisms of cellular dysfunction resulting from altered protein post-translational modifications, with a focus on protein carbonylation due to lipid peroxidation and protein acylation due to altered liver metabolism. His academic interests encompass proteomics, sirtuins, acetylation, alcohol-associated liver disease, and diabetic nephropathy. Key publications include "An overview of the chemistry and biology of reactive aldehydes" (2013), "The human sirtuin family: evolutionary divergences and relevance to human pathology" (2011), "Chronic ethanol consumption induces mitochondrial protein hyperacetylation in the kidney" (2015), "4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification" (2011), "Protein carbonylation in a murine model for early alcoholic liver disease" (2012), and "Lipid Peroxidation Derived Reactive Aldehydes in Alcoholic Liver Disease" (2019). His scholarship has amassed over 3,200 citations, underscoring substantial influence in oxidative stress and metabolic pathology research. Fritz received the Excellence in Toxicology Doctoral Teaching Award and serves as a board member of the Colorado Biological Mass Spectrometry Society. He contributes to the CU Center for Drug Discovery, specializing in pathogenic mechanisms of alcohol-associated liver disease.