Rate My Professor Kirsten Coupland

Coupland's research examines the composition and dynamics of cerebrospinal fluid (CSF) and interstitial fluid in brain health and diseases, particularly ischaemic stroke, where she is Australia's sole researcher dedicated to CSF's role in outcomes. Her investigations cover elevated intracranial pressure post-stroke, reduced CSF efflux, molecular mechanisms of hypothermia neuroprotection, CSF and brain proteome changes, statin protection, and peri-infarct depolarisations. She has secured over $2.16 million in funding, including NHMRC Ideas Grants as CIA and partnerships with CSL. Awards include the 2021 Cardiovascular Research Network Mid-career researcher award, HMRI Early Career Research Fellowship in Stroke (2017-2022), and several presentation prizes. Key publications include "Brain fluid physiology in ischaemic stroke; more than just oedema" (Fluids and Barriers of the CNS, 2025), "Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats" (Frontiers in Neurology, 2021), "Role of NOTCH3 Mutations in the Cerebral Small Vessel Disease Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy" (Stroke, 2018), and "Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease" (PLoS ONE, 2016). She teaches courses in pharmacology and experimental design and supervises postgraduate students, contributing to stroke therapy advancements through collaborations with international researchers and clinicians.