
Fosters a love for lifelong learning.
Joshua L. Price is Professor in the Department of Chemistry and Biochemistry at Brigham Young University, where he joined as Assistant Professor in 2011, was promoted to Associate Professor in 2017, and to full Professor in 2022. Listed under Organic Chemistry on the department faculty directory, his research centers on bioorganic chemistry, including protein folding and structure, the energetic and structural effects of protein glycosylation, PEGylation, and stapling, as well as design of novel proteins using unnatural amino acids. Price earned a B.S. in Biochemistry from Brigham Young University in 2003, summa cum laude with University Honors. He received his Ph.D. in Chemistry from the University of Wisconsin-Madison in 2008 under Professor Samuel H. Gellman, with a dissertation on the development of α/β-peptide foldamer tertiary and quaternary structure. From 2008 to 2011, he held an NIH Ruth L. Kirschstein NRSA Postdoctoral Fellowship at The Scripps Research Institute under Professor Jeffery W. Kelly, focusing on stabilizing protein native states by N-glycosylation of enhanced aromatic sequons in reverse turns.
Price's key publications include foundational work such as Culyba, E. K. et al., 'Protein Native State Stabilization by Placing Aromatic Side Chains in N-Glycosylated Reverse Turns' (Science, 2011); Price, J. L. et al., 'Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contexts' (Proc. Natl. Acad. Sci. USA, 2011); and Price, J. L. et al., 'Context-Dependent Effects of Asparagine Glycosylation on Pin WW Folding Kinetics and Thermodynamics' (J. Am. Chem. Soc., 2010). Recent contributions feature Xiao, Q. et al., 'Structural guidelines for stabilization of α-helical coiled coils via PEG stapling' (RSC Chem. Biol., 2022); Stern, K. L. et al., 'Prerequisites for Stabilizing Long-Range Synergistic Interactions among b-, c-, and f-Residues in Coiled Coils' (Biochemistry, 2022); and Xiao, Q. et al., 'Long-range PEG stapling: macrocyclization for increased protein conformational stability and resistance to proteolysis' (RSC Chem. Biol., 2020). Among his honors are the Hirschmann/Rich Graduate Award in Bioorganic Chemistry (2008), NIH Chemistry-Biology Interface Training Grant Fellowship (2004-2007), Barry M. Goldwater Scholarship (2002-2003), and Outstanding Teaching Award from BYU College of Physical and Mathematical Sciences (2022). He has served on the BYU pre-health advising committee since 2011 and as an ad hoc reviewer for journals and funding agencies.