Rate My Professor Jennifer Cremins

Jennifer Cremins is an associate professor and Dean's Faculty Fellow in Bioengineering and Genetics at the University of Pennsylvania, where she established the Cremins Lab in 2014 to explore the principles of chromatin folding that encode neuronal cell fate commitment and synaptic plasticity. The lab employs chromosome-conformation-capture methods, high-throughput sequencing, computational modeling of 3D chromatin structures, and genetic perturbations to link genome architecture with epigenetic states and gene expression patterns during neural development and in disease contexts such as Fragile X syndrome and Alzheimer's disease. Cremins investigates how disruptions in chromatin organization contribute to neurodevelopmental and neurodegenerative disorders, aiming to engineer chromatin topologies for therapeutic interventions in neural regeneration. She earned a B.S. in Chemical Engineering from Clarkson University in 1999 and a Ph.D. in Biomedical Engineering from the Georgia Institute of Technology in 2007. Throughout her tenure at Penn, spanning 2014 to 2025, she held appointments in the Department of Bioengineering in the School of Engineering and Applied Science, the Department of Genetics in the Perelman School of Medicine, and the Epigenetics Institute.