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Jacqueline Bentel, PhD, is a researcher in anatomical pathology associated with PathWest Laboratory Medicine at Fiona Stanley Hospital, Murdoch, Western Australia. She has previously supervised doctoral and honours research at Murdoch University, including a 2006 PhD thesis on FLJ22318 as a novel binding partner of the NKX3-1 prostatic tumour suppressor and an honours project on regulation of ETS1 expression in prostate cancer cells. Bentel has affiliations with Royal Perth Hospital and the University of Western Australia Division of Pathology, School of Surgery and Pathology. Her academic contributions span molecular biology and cancer research, with offprint requests directed to Murdoch University in early publications such as the 2004 study on inhibition of MCF-7 breast cancer cell proliferation by 5alpha-6alpha-epoxy-androsterone.
Bentel's research specializations include circulating tumour DNA and cells for cancer detection, staging discordance in uveal melanoma, genomic sequencing in melanoma, microRNA regulation in prostate cancer, and pathological features of lung adenocarcinoma and renal cell carcinoma. Key publications co-authored by her are 'Discordance between clinical and post-surgical staging of uveal melanoma' (The Lancet Oncology, 2022), 'Discordance between clinical and pathologic staging and pathological features of uveal melanoma' (Asia-Pacific Journal of Clinical Oncology, 2023), 'Detection of metastases using circulating tumour DNA in uveal melanoma' (Journal of Cancer Research and Clinical Oncology, 2023), 'Low-Pass Whole-Genome Sequencing as a Method of Detecting Circulating Tumor DNA in Melanoma' (Journal of Molecular Diagnostics, 2020), 'Analysis of Circulating Tumour Cells in Early-Stage Uveal Melanoma' (Cancers, 2021), 'miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression' (Oncotarget, 2017), 'Case report: unusual discovery and first presentation of a KRAS mutated lung adenocarcinoma' (Pathology, 2015), and 'Androgen regulation of the prostatic tumour suppressor NKX3.1' (Biochemical Journal, 2012). These works involve collaborations with researchers from Edith Cowan University, Harry Perkins Institute of Medical Research, Lions Eye Institute, and Erasmus MC, contributing to advancements in oncology diagnostics and metastasis detection through techniques like immunohistochemical analysis and whole-genome sequencing.

Photo by Osarugue Igbinoba on Unsplash
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