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University of Sydney
Brings passion and energy to teaching.
Inspires students to love learning.
Brings enthusiasm and expertise to class.
Always goes the extra mile for students.
Great Professor!
Iain Campbell is Professor Emeritus in the School of Life and Environmental Sciences at the University of Sydney, within the Faculty of Science. He earned a BSc (Hons) and a PhD in Biochemistry from the University of Sydney, with his doctoral studies spanning 1979 to 1983. As Professor of Molecular Biology, Campbell has made substantial contributions to neuroimmunology, with research interests centered on neuroinflammation, cytokine signaling—particularly interleukin-6 (IL-6) and interferon-α (IFN-α)—microglia phenotypes and responses, neurodegeneration, and glial cell functions in central nervous system diseases. His laboratory employs transgenic mouse models, such as GFAP-IL6 mice, to investigate these mechanisms.
Campbell's career at the University of Sydney includes serving as Professor of Molecular Biology from 2004 and Head of the School of Molecular Bioscience from January 2011 to January 2016. He has published 377 papers, accumulating 26,150 citations and achieving an h-index of 94 according to Google Scholar metrics. Notable publications include 'Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain' (2014, Journal of Neuroscience), 'Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α' (2022), 'The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies' (2024), 'Interferon-α receptor antisense oligonucleotides reduce neuroinflammation and neuropathology in a mouse model of cerebral interferonopathy' (2024), and 'Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling' (2024). His work elucidates distinct microglia responses to cytokines and phosphoproteomic landscapes in interferon responses within the brain and glial cells. Campbell's verified professional email is iain.campbell@sydney.edu.au.
Professional Email: iain.campbell@sydney.edu.au