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Professor George Christophides is the Professor of Infectious Diseases & Immunity in the Department of Life Sciences within the Faculty of Natural Sciences at Imperial College London. He earned his PhD in Molecular Biology from the University of Athens in 1994, serving as a research assistant at the university during his doctoral studies. Following his PhD, he moved to the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, where he held positions as a Marie Curie Research Fellow, research associate, and staff scientist. In 2005, Christophides joined Imperial College London, progressing to his current professorial appointment. His career has been dedicated to advancing understanding of vector-borne diseases through rigorous molecular and immunological research.
Christophides specializes in infectious diseases and immunity, focusing on mosquito biology, malaria vectors, and innate immune mechanisms. His research seeks to identify and harness mosquito genes that inhibit the development of the malaria parasite Plasmodium, with the ultimate aim of engineering malaria-resistant mosquitoes. As co-lead of the Transmission:Zero programme at Imperial College London, he has driven innovations in gene drive technologies for malaria vector control. Key contributions include the engineering of mosquitoes incapable of spreading malaria, the production of the first transgenic mosquitoes in Africa, and demonstrations of gene-drive-capable mosquitoes suppressing patient-derived malaria infections. With over 330 peer-reviewed publications and more than 16,000 citations as documented on ResearchGate, his work has profoundly influenced global efforts in malaria elimination. Christophides collaborates on major initiatives such as Target Malaria and the Network of Excellence in Malaria, contributing to sustainable strategies against vector-borne diseases. His expertise extends to editorial roles and international scientific committees in the field.