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Associate Professor Fei Liu serves in the School of Natural Sciences within the Faculty of Science and Engineering at Macquarie University. She obtained her BSc in Chemistry from John Carroll University and her PhD in Organic Chemistry from Yale University. After completing her doctoral studies, she undertook postdoctoral training as an NIH postdoctoral fellow at Harvard University. In 2004, she relocated from Boston to Sydney and joined Macquarie University as a Senior Lecturer in the Department of Chemistry and Biomolecular Sciences, where she later advanced to her current position as Associate Professor.
Fei Liu's research specializations encompass asymmetric and catalytic reactions to enable proficient bond formation and stereocontrolled generation of synthons or biological probes; isozyme-specific antagonist discovery through conformational selection; the chemistry and biology of post-translational modifications of enzymes or proteomes in cell signaling; and the development of efficient synthetic methods for small molecules with applications in chemistry and biology. She applies chemical proteomics, in collaboration with the Australian Proteome Analysis Facility, to advance basic biological discovery and medicine. Her scholarly contributions include 71 research outputs, comprising 52 articles and 7 review articles, with notable publications such as 'Divergent response of homologous ATP sites to stereospecific ligand fluorination for selectivity enhancement' (Organic & Biomolecular Chemistry, 2017), 'Cooperative Trifunctional Organocatalysts for Proficient Proton Transfer Reactions' (Chemical Record, 2017), 'Systems Proteomics View of the Endogenous Human Claudin Protein Family' (Journal of Proteome Research, 2016), 'Trifunctional Organocatalysts: Catalytic Proficiency by Cooperative Activation' (European Journal of Organic Chemistry, 2015), and 'Quantitative chemical proteomics in small scale culture of phorbol ester stimulated basal breast cancer cells' (Proteomics, 2011). Her work has accumulated 1138 citations and an h-index of 20. Liu has participated in 36 research projects, including five active ones on adenoid cystic carcinoma, zero net emissions from agriculture, automated monitoring systems for bugs, degrader technology for motor neuron disease, and light-controlled chemical sequestration of proteins. She has garnered media coverage for the CRC-P The ProbioTICK Initiative (2017) and contributes to economic impact through Hyperdrive Science Pty Ltd. She received the NIH postdoctoral fellowship.
