Rate My Professor Evan Ingley

Ingley's research has produced significant publications in leading journals. Key works include 'Functions of the Lyn tyrosine kinase in health and disease' (Biochemical Journal, 2012), which explores the multifaceted roles of Lyn in cellular signalling; 'The SH2 interactome: Development and utility of a phospho-tyrosine-specific yeast two-hybrid system to identify and analyse signalling pathways' (2020); 'Crystal structures of the Lyn protein tyrosine kinase domain reveal a novel activating conformation and unique autophosphorylation sites' (Journal of Biological Chemistry, 2009); 'MADM, a novel adaptor protein that mediates receptor to Ras/MAPK activation' (Journal of Biological Chemistry, 2002); 'SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 recruitment' (Cell Reports, 2021); 'Lyn kinase plays important roles in erythroid expansion, maturation, and survival' (Biochemical Journal, 2016); and 'Identification of novel sarcoma risk genes using a two-stage genome-wide association study' (Journal of Medical Genetics, 2019). These contributions have advanced knowledge of Lyn kinase activity in erythroleukemia cell survival, sarcoma genetics, and phospho-tyrosine interactomes. His studies on topics like injury-initiated atherogenesis and novel protein kinase substrates further demonstrate his impact on understanding signalling pathways in disease contexts. Ingley's work underscores the importance of precise kinase regulation in cellular homeostasis and pathology.