Rate My Professor Eva-Stina Edholm

Edholm's research centers on fish immunology and vaccinology, focusing on unconventional, innate-like T and NKT cells, MHC class I-like molecules, and their roles in antiviral immunity in Atlantic salmon. Utilizing CRISPR/Cas9 gene editing, MHC tetramer technologies, and next-generation sequencing, her work explores early immune surveillance against viruses such as salmonid alphavirus (SAV3) and piscine orthoreovirus (PRV). Key publications include 'Profiling the T Cell Receptor Alpha/Delta Locus in Salmonids' (Frontiers in Immunology, 2021), 'Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon' (Vaccines, 2021), 'Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection' (Viruses, 2019), 'Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus' (Carcinogenesis, 2019), 'Microbial danger signals control transcriptional induction of distinct MHC class I L lineage genes in Atlantic salmon' (Frontiers in Immunology, 2019), and 'Comparative analysis of salmonid non-classical MHC class I L lineage genes' (Developmental and Comparative Immunology, 2025). She contributes to projects like CRISPRized Immortality, ImmunDNA, and AquTRep, and serves on the editorial board of Comparative Immunology Reports, with editorial roles in Frontiers in Immunology. Her research has garnered over 2200 citations, influencing comparative immunology in ectothermic vertebrates and aquaculture vaccine development. She participated in the UiT Aurora Outstanding program for talented researchers.