Rate My Professor Erica Mandell

Dr. Mandell's research centers on bronchopulmonary dysplasia (BPD) and associated pulmonary hypertension, antenatal inflammation, vitamin D deficiency and therapeutic interventions, lung development, pulmonary vascular phenotypes, and ventilator-induced lung injury. Her investigations examine the impacts of antenatal endotoxin, intraamniotic exposures such as sFlt-1, and maternal vitamin D deficiency on lung structure, function, and vascular growth in experimental models. She explores pulmonary vasodilator strategies, disease phenotyping in severe BPD including dysanapsis, cholestasis, and thrombocytopenia, and perinatal hypoxia-inducible factor stabilization to preserve alveolar and vascular growth. Key publications include 'Development of late pulmonary hypertension after antenatal inflammation in experimental bronchopulmonary dysplasia' (Pediatr Res, 2025), 'Intraamniotic vitamin D preserves lung development and prevents pulmonary hypertension in experimental bronchopulmonary dysplasia due to intraamniotic sFlt-1' (Am J Physiol Lung Cell Mol Physiol, 2025), 'Bronchopulmonary Dysplasia–Associated Pulmonary Hypertension: Basing Care on Physiology' (Neoreviews, 2024), 'Dysanapsis as a Determinant of Lung Function in Development and Disease' (Am J Respir Crit Care Med, 2023), 'Persistent pulmonary hypertension of the newborn' (Pediatr Pulmonol, 2021), and 'Vitamin D Deficiency in Development: How Much Is Enough, and How Much Is Too Much?' (Am J Respir Cell Mol Biol, 2021). She has presented on topics such as 'Vitamin D Role in Lung Disease and Development' in the Pediatrics Basic & Translational Research Seminar Series and contributes to the Neonatology Basic Science fellowship program, focusing on lung growth, pulmonary vascular function, and clinical trials involving inhaled nitric oxide.