Rate My Professor David Harris

Professor David Harris, AM, MD, MBBS, FRACP, is Professor of Medicine at the University of Sydney, with appointments in the Westmead Clinical School and as an Adjunct Professor in Sydney Medical School. He serves as Director of Nephrology and Dialysis in the Western Sydney Renal Service and Director of the Renal Failure Laboratory in the Centre for Transplantation and Renal Research at the Westmead Institute for Medical Research. His career highlights clinical leadership and research excellence in nephrology, beginning as a registrar at Westmead Hospital in 1982. Harris's research focuses on the prevention and management of chronic kidney disease (CKD), investigating mechanisms of progression including renal tubular hypermetabolism, proteinuria-induced injury, oxidative stress, NF-κB activation, epithelial-mesenchymal transition, matrix metalloproteinases, interstitial inflammation, and kidney fibrosis. His laboratory explores novel therapies such as regulatory lymphocytes, macrophages, dendritic cells, DNA vaccination, and immune modulation to halt CKD progression. Clinically, he studies peritoneal and haemodialysis outcomes, contributing to trials like the CKD-FIX study on allopurinol and a randomized controlled trial for slowing progression in autosomal dominant polycystic kidney disease.