Rate My Professor Daniel Nietlispach

Key methodological advancements from his laboratory include compressed sensing reconstruction techniques for multidimensional NMR spectra, enabling higher resolution from undersampled data (Bostock, Holland, and Nietlispach, Journal of Biomolecular NMR, 2017), and adaptable phospholipid membrane mimetics using saposin nanoparticles for NMR studies of membrane proteins (Chien et al., Journal of the American Chemical Society, 2017). Prominent publications feature investigations into partial agonism via multiple equilibria in the β1-adrenergic receptor (Solt et al., Nature Communications, 2017), conformational plasticity of ligand-bound GPCR complexes using 19F NMR (Frei et al., Nature Communications, 2020), and characterization of denatured states of sensory rhodopsin II (Tan et al., Journal of Molecular Biology, 2019). Additional contributions encompass the role of NMR in mapping GPCR conformational landscapes (Bostock, Solt, and Nietlispach, Current Opinion in Structural Biology, 2019). Nietlispach's scholarly impact is evidenced by over 6,485 citations and an h-index of 42, reflecting his substantial influence on biomolecular NMR and membrane protein structural biology within the School of the Biological Sciences.