Rate My Professor Christopher Corpe

Dr Christopher Corpe is a Senior Lecturer in Nutritional Sciences in the Department of Nutritional Sciences within the Faculty of Life Sciences & Medicine and School of Life Course & Population Sciences at King’s College London. He holds a D.Phil. in Biology from the University of York. Corpe’s research in Health Science centers on sugars, sweeteners, and vitamin C, examining the mechanisms by which these nutrients are transported across the small intestine. His investigations include the role of intestinal sugar sensor mechanisms, such as T1R2/3, in regulating sugar transport and incretin secretion; identification of polyphenols that blunt postprandial glycemia; and the metabolic effects of sugars and high-intensity non-nutritive sweeteners. To pursue these goals, he utilizes in silico approaches including molecular docking and systematic review and meta-analysis, in vitro gut models like Caco-2 and GLUT-ag cells, animal models such as Xenopus oocytes, ZDF rats, and mouse knockouts, and human interventional studies.

At King’s College London, Corpe has served as Lecturer in Nutritional Sciences since September 2009, advancing to Senior Lecturer. His work elucidates the molecular mechanisms of intestinal sugar transport via SGLT1, GLUT2, and GLUT5, regulation by dietary carbohydrates, metabolic consequences of postprandial sugar flux, and gut sensing of processed sugars and artificial sweeteners influencing gastrointestinal satiety peptides. Key publications encompass collaborations on noncoding RNAs in cancer, including “CircHPCAL1 promotes the progression of pancreatic cancer via the regulation of STEAP2” (2025, Clinical and Translational Medicine), “RNA profiling and immunohistochemistry analyses of circRNAs in imatinib-resistant gastrointestinal stromal tumors” (2025, Journal of Translational Medicine), “Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR-769-3p and interaction with GOLM1” (2024, Clinical and Translational Medicine), and studies on inflammation in ischemic stroke patients with type 2 diabetes (2024, Advanced Neurology). His research outputs have garnered 900 citations on the King’s College London Research Portal.