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5.04/23/2026

Helps students see the bigger picture.

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About Carrie

Carrie L. Lucas is an Associate Professor of Immunobiology at Yale University School of Medicine. She earned her PhD from Harvard University in 2011 and her BS from the University of North Carolina at Chapel Hill in 2006, followed by postdoctoral training at the National Institutes of Health, NIAID, which she completed in 2016. Since establishing her laboratory in 2016 within the Department of Immunobiology, Dr. Lucas has focused on discovering single-gene defects underlying severe immune disorders in humans. Her research employs human genomics, in vitro studies with primary patient cells, and in vivo genetically engineered mouse models to elucidate genetic, cellular, and biochemical mechanisms driving rare immune disorders. These efforts illuminate fundamental principles of immunology relevant to diagnoses and treatments. Her research interests encompass hereditary autoinflammatory diseases, immunologic deficiency syndromes, immunoproliferative disorders, inflammation, signal transduction, T-lymphocytes, and phosphoinositide 3-kinase (PI3K) signaling pathways, particularly in immunodeficient patients with PI3K mutations.