Rate My Professor Caleb Webber

Webber’s contributions span single-cell transcriptomics, genomic analyses, and cellular modeling of neurodegeneration. Recent publications include 'Changes in neural progenitor lineage composition during astrocytic differentiation of human iPSCs' (eLife, 2025, with Z. Li et al.), 'Modeling common Alzheimer’s disease with high and low polygenic risk in human iPSC: A large-scale research resource' (Stem Cell Reports, 2025, with E. Maguire et al.), 'A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease' (Nature Communications, 2024, with S. Tsartsalis et al.), 'Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression' (Bioinformatics Advances, 2024, with I. Nassiri et al.), and 'Spatial mapping of genetic liability to psychiatric disorders in the adult human hippocampus' (Biological Psychiatry: Global Open Science, 2026, with Y. Baran et al.). Earlier influential papers encompass 'Epistasis in neuropsychiatric disorders' (Trends in Genetics, 2017) and 'Forging links between human mental retardation-associated CNVs and mouse gene knockout models' (PLoS Genetics, 2009). Previously at the University of Oxford, including the Oxford Parkinson’s Disease Centre, Webber joined the UK DRI at Cardiff University to advance these efforts.