Rate My Professor C Vignesh Kumar

Dr. Vignesh Kumar's research interests include Aging, Cellular Proteostasis, Downstream Processing, protein chaperones such as DnaK, Sse1, Hsp110, substrate-chaperone interactions, protein aggregation and disaggregation, and endoplasmic reticulum stress. He has published 8 papers in international journals and co-authored the book chapter 'Hsp70: A Multi-Tasking Chaperone at the Crossroad of Cellular Proteostasis' in Regulation of Heat Shock Protein Responses, Heat Shock Proteins Vol. 13 (Springer, pp. 251-274, 2018). Key publications encompass 'Monitoring conformational heterogeneity of the lid of DnaK substrate-binding domain during its chaperone cycle' (The FEBS Journal, 2016), 'Information encoded in non-native states drives substrate-chaperone pairing' (Structure, 2012), 'Unique structural modulation of a non-native substrate by cochaperone DnaJ' (Biochemistry, 2013), 'Interdomain communication suppressing high intrinsic ATPase activity of Sse1 is essential for its co-disaggregase activity with Ssa1' (The FEBS Journal, 2020), and 'Sse1, Hsp110 chaperone of yeast, controls the cellular fate during endoplasmic reticulum stress' (G3: Genes, Genomes, Genetics, 2024). His scholarly output has accumulated 151 citations. Additionally, he is the Principal Investigator for a DRDO-sponsored research project.