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5.04/23/2026

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About Bradford

Bradford Smith is an Associate Professor in the Department of Bioengineering at the University of Colorado Denver's Anschutz Medical Campus, part of the College of Engineering, Design and Computing. He leads the Pulmonary Biomechanics Lab, focusing on the pathogenesis and treatment of acute respiratory distress syndrome and ventilator-induced lung injury. His research integrates in vivo models of lung injury, computer-controlled mechanical ventilation, immunohistochemistry, electron microscopy, design-based stereology, electrical impedance tomography, biochemical assays, and multi-scale computational models. These approaches elucidate how fluid-mechanical stresses and surface tension forces in alveoli contribute to cellular-scale injury and organ-scale dysfunction. Smith develops innovative ventilation strategies, devices, and algorithms to mitigate ventilator-induced lung injury in critical care settings.