36 research specialist jobs found in Baltimore, MD

Job Req ID:  98737 We are seeking a Research Specialist II who will work on funded projects related to the study of the mechanisms and target identification for Huntington’s Disease and will provide lab support for ongoing clinical studies for HD. Under the supervision of a faculty investigator, the research specialist works independently to carry-out research experiments, involving a range of sophisticated assays using modern molecular biology, protein biochemistry and cell biology techniques. Makes significant/important contributions to various aspects of research efforts. Executes independent decision making and trouble-shooting during experiments and participates in designing new methodologies. Utilizes specialized knowledge to interpret results and participates in planning new experimental approaches towards research goals. Uses scientific knowledge and lab experience to make judgments and decisions. Makes scientific contribution to protocol development,...

Job Req ID:   108122 The Department of Neurology is seeking a Research Specialist  who will work in a stem cell lab in support of cutting-edge human stem cell work in the area of neurodegeneration. The successful candidate will be performing routine stem cell work and following protocols under close supervision. Will work with all members of the lab and will assist as needed in aseptic cell culture techniques, histology and various additional biochemical techniques. General day-to-day laboratory maintenance and general lab upkeep are also required. Will work under Biosafety levels 1, 2 and 3. Regularly and routinely responsible for administrative and scientific activities of both the Stem Cell Core and the research labs of Dr. Maragakis. This includes project development, invoice payments, reimbursements, service contract procurement and payment, equipment maintenance, animal surgery suite management, budgeting, manuscript compos. Oversee data...

Job Req ID:  108546 Multidisciplinary vision laboratory seeks a motivated Research Specialist to help coordinate and perform research that characterizes and improves outcomes of primary cell culture from several ophthalmic issues, including glaucoma disease Specific Duties & Responsibilities Responsible for inventory, culture, proliferation, and classifying primary cell tissue in culture. Confocal and multiphoton microscopy of immunohistochemical studies of explanted mouse or human ocular tissues. Perform various glaucoma model and optic nerve ophthalmic surgeries and intraocular injections in mice and rats, preparing and dosing animals in drug studies, measuring intraocular pressures via rebound tonometry, using injectable and/or gas anesthetics via commercial rodent anesthesia machine in accordance with USDA and AALAC. Histological methods performed in this position include cryopreservation and epoxy preparation (embedding and sectioning) and...

Job Req ID:   104739 We are seeking a Research Specialist . The laboratory uses cell culture and animal models to study mechanisms that enable organisms to adapt to energy and metabolic stresses (physical exercise, diet). The Research   Specialist will conduct scientific research, manage mouse colonies and assist in laboratory organization. Will have a working understanding of the context and implications of the research in order to apply and interpret theoretical knowledge necessary to conduct research. The range of duties includes, but is not limited to: experimental design, developing methodology, conducting procedures, modifying procedures as needed, data collection and analysis, mouse colony management and laboratory organization. Specific Duties & Responsibilities Assist in research projects with experimentation, using cell and molecular biology techniques (tissue culture; DNA, RNA and protein isolation; RT-PCR and...

Job Req ID:  108980 We are seeking a Sr. Research Specialist. Position requires a proficient and experienced laboratory scientist with a solid foundation in molecular biology and tissue culture. Experience with rodent experiments will be a plus. After introduced to the techniques and platforms, the successful candidate can conduct research independently or with minimal supervision. With limited supervision by the PI, this individual will design and perform laboratory experiments, analyze data, and may also contribute to manuscripts. This position will provide training to other individuals who may be assigned to the laboratory on a regular or temporary basis. Specific Duties & Responsibilities Performs routine and complex research laboratory, including sterile cell culture, molecular biology techniques and small rodent handling. Independently processes and analyzes data, formulates conclusions and creates appropriate statistical presentations, including...

Job Req ID:  108967 The lab studies the role of hypoxia in the development of metastasis. The laboratory utilizes 2D and 3D cell culture, a novel hypoxia fate-marking mouse model recently developed in the lab, high-resolution/high-content microscopy, biochemistry, molecular biology, and bioinformatics approaches to decipher the role of hypoxia in cancer spread to identify therapeutic strategies and potential prognostic markers. We are seeking a Research Specialist who will be an active member of a dynamic, team-oriented, and expanding research group. The candidate will also participate in the development of novel animal models to investigate metastatic spread. This laboratory position requires experience in basic laboratory techniques in molecular biology, tissue culture and animal handling.  Must perform assay development independently. Familiarity with flow cytometry is desirable. Specific Duties & Responsibilities Responsibility for planning,...

Job Req ID:  107578 Department of Psychiatry and Behavioral Sciences is seeking a Research Specialist to focus on investigating pathogenic pathways and finding novel therapeutic targets for neuropsychiatric disorders, including schizophrenia and related disorders. May make contributions to various aspects of research efforts. May include some routine trouble shooting, and independent decisions. Specific Duties & Responsibilities Molecular and biochemical assays on cells and rodent and human tissues. Tasks will include protein, RNA and DNA extraction and purification, cell transfection, Western blotting, immunohistochemistry and immunofluorescence, and molecular cloning. Cell culture involving multiple cell types, including iPSCs. Potential role in genome editing project involving generation of edited human iPSC lines. Assistance with routine lab operations, including ordering laboratory supplies, compliance with regulatory requirements, care and...

Job Req ID:  108975 The Johns Hopkins University Department of Otolaryngology is seeking an experienced Sr. Research Specialist who will work under the general supervision of Dr. Andrew Lane and assist in the overall operation of his laboratory. The individual will work closely with the Principal Investigator on various lab projects and conduct experiments related to sinusitis and olfaction.  Participation in research conferences and the opportunity to perform own experiments within the context of laboratory projects are encouraged. There is the potential for authorship, and the lab has a history of including students and laboratory staff on abstracts and publications. Specific Duties & Responsibilities: Works with Principal Investigator to design, conduct, and analyze scientific experiments and to help with manuscript and grant preparation. Perform sophisticated data analysis utilizing extensive knowledge base and varied methods experience....

Job Req ID:  98356 We are seeking a highly motivated Research Specialist II  who is interested to join our team to work on the in vitro and in vivo testing of brain gene therapy candidates. The Research Specialist II will participate in the development and testing of gene transfer methods for the mouse brain. She/he will be working in a team that includes other technicians, graduate students and postdoctoral fellows and will make significant and important contributions to various aspects of these research efforts. This will include neuronal cultures, rodent injections, genotyping, gene expression measurement qPCR, and immunoblotting/immunohistochemistry for protein expression. Our laboratory investigates the mechanisms of synaptic plasticity and how defects in this process cause intellectual disability, autism, and epilepsy. We use a wide spectrum of techniques (molecular biology, biochemistry, cell biology, mouse genetics, histology, in vitro/in vivo imaging, omics...

Job Req ID:  106717 The Cochella lab is looking for a Research Specialist who will join a young and dynamic, international, scientific community to tackle questions related to regulation of gene expression during development and disease. The main responsibilities will be ensuring the smooth day-to-day running of the laboratory (including managing supplies and reagents), molecular biology work, and work with the nematode Caenorhabditis elegans (such as managing a frozen strain collection, microinjection, microscopy and genetics). For interested candidates there will be opportunities to pursue an independent research project, and a chance to make an important contribution to basic biomedical research. Specific Duties & Responsibilities Perform a range of assays and experiments specific to area of research, which will include handling C. elegans and generating transgenic lines, molecular cloning, immunostaining, in situ hybridization and microscopy,...

Job Req ID:   108888 We are seeking a Research Specialist to join the Kebschull Lab, an exciting and fast-paced Molecular Neuroscience Laboratory in Biomedical Engineering. The laboratory is active in two research areas: 1) Development of new sequencing and viral tools to map brain circuits.2) Understanding changes to neuronal circuits across different disease states, including drug addiction, and evolution. To do so, the laboratory uses molecular biology and synthetic biology approaches with a focus on spatial sequencing and cellular barcoding. Specific Duties & Responsibilities Conduct scientific research, especially focused on spatial transcriptomics and microscopy. Have a working understanding of the context and implications of the research in order to apply and interpret theoretical knowledge necessary to conduct research Duties includes, but is not limited to: experimental design, developing methodology,...

Job Req ID:  109332 The Department of Neurology is seeking a Research Specialist for the Cutaneous Nerve Laboratory. The Cutaneous Nerve Laboratory is a CAP accredited, dynamic 15-member lab that works collaboratively to study nerve fibers and proteins in the skin. We deal with clinical samples, clinical research projects, animal model-based research and serve as a core laboratory for world-wide clinical trials. Under the general supervision of a faculty investigator or laboratory supervisor, the Research Specialist is responsible for performing routine analyses and tests on human skin tissue. This position requires use of scientific methods, standard operating procedures, and techniques gained through training and experience. The Reasearch specialist utilizes specialized knowledge to interpret results. This person applies analytical skills to implement assigned projects, and to identify and troubleshoot situations needing special attention. The lab is responsible for...

Job Req ID:   100936 We are seeking a Research Specialist who will be studying cellular and molecular metabolism. Under the general supervision of a faculty investigator or laboratory supervisor, a highly motivated individual is responsible for conducting experiments to advance scientific knowledge in the area of metabolic biochemistry and genetics. The Research Specialist will likely serve as the lead bench scientist on one or more projects at a time, while also performing other tasks that are related to other ongoing projects in the lab or on tasks that are for the overall benefit of the lab and its members. In their efforts, they will be expected to make significant contributions to research efforts which may include troubleshooting, exercising independent judgement while participating in the planning of experiments, and the training/guidance of other individuals who may be assigned to the laboratory on a regular or temporary basis. Additionally, this will...

Job Req ID:   107525 The Enterics Laboratory at Johns Hopkins University is seeking a full-time Research Specialist ll  to assist with ongoing projects in the lab. This position would involve providing laboratory, analytical and administrative assistance for several large studies involving collaborations from institutions worldwide. The group is currently studying adult diarrheal disease in Cameroon, the genomic epidemiology of cholera in Africa and cholera diagnostic evaluation and vaccine trials in cholera endemic areas among other things. A successful candidate must be able to work independently and under limited supervision. Specific Duties & Responsibilities The position involves a mixture of laboratory work, data analysis and international travel to train our partners on laboratory techniques relevant to the research. Laboratory duties include microbiology (i.e. culture and identification of specific bacteria), ELISA,...

Job Req ID:  108848 We are seeking a proficient Sr. Research Specialist with a sophisticated understanding of basic techniques and a solid foundation in carrying out research tasks gained from experience is required for this role.  Must have great attention to detail, excellent writing techniques and effective communication skills.  Apply independent thought to make decisions with PI. Specific Duties & Responsibilities 50% of time performs clinical and research lab experiments and tests. Follows established procedures and protocols, utilize appropriate technique to design and perform clinical and laboratory test/experiments. 25% of time participates in tissue bank-related tasks or animal experiments. 5% of time participate in drafting and submitting IRB, MTA applications, and research progress report. 5% of time reports and records outcomes/results of all tests. 5% of time responsible for operational activities such as; performing...

Job Req ID:  107980 We are seeking a highly motivated Research Specialist II who is interested to join our team. The Research Specialist II will participate in the study of the genetic basis of Parkinsons disease, with hopes of identifying potential therapeutic targets for developing PD treatments. The employee will be working on a team that includes other technicians, graduate students and postdoctoral fellows and will make significant and important contributions to various aspects of these research efforts. Our laboratory uses a wide spectrum of techniques (molecular biology, biochemistry, cell biology, mouse genetics, histology, imaging) to study the molecular mechanisms of neurodegeneration of Parkinsons disease, nitric oxide signaling and neuronal cell death and neuroprotective and neurorestorative strategies in neurodegenerative diseases, stroke and trauma.  www.theDawsonlab.org Specific Duties & Responsibilities Make scientific contribution to...

Job Req ID:  106117 We are seeking a Sr. Research Specialist who is highly motivated, energetic and an independent individual, with an interest in developmental biology and breast cancer to work in a fast-paced and dynamic basic science lab. The Ewald Lab studies the molecular control of cancer metastasis through a combination of advanced 3D culture models and both genetically engineered (GEMM) and patient derived (PDX) models of cancer metastasis. Specific Duties & Responsibilities Design and management of both the GEMM and PDX animal colonies, which involves working independently with graduate students, postdoctoral fellows, and clinical fellows to identify strains of mice, genotypes, and patient tumor subtypes necessary for their work. Maintenance of this >300 cage mouse colony involves planning and setting up breeding's, weaning mice, tagging, tailing, and genotyping mice. The cancer models require specialized data collection on tumor progression in...

Sr. Research Specialist The purpose of our laboratory research in the Department of Genetic Medicine is to elucidate molecular disease mechanisms and test therapies for a group of rare diseases that disrupt epigenetics and chromatin. We are seeking a Sr. Research Specialist who will do the following. Independently work in a translational epigenetics/chromatin research lab using mouse models and human stem cell-based culture models. Identify, develop, and optimize assays and protocols. Design independently implements experimental approaches for research projects. Perform a wide range of sophisticated assays, including preparation of samples for next-generation sequencing approaches (i.e., RNA-seq, ChIP-seq, whole genome bisulfite sequencing, and/or similar methods). Requires significant and important contributions to various aspects of research efforts, including troubleshooting, independent decision-making, and training/guidance of other lab personnel including students,...

Job Req ID:  107958 This position requires a proficient and experienced Research Specialist to work in a busy immunology core facility specializing in flow cytometry, cell sorting, and multiplex biomarker assays using Luminex and ELISA. Experience in one or more of these techniques is desired but not required. After initial training, the successful candidate will work independently or with minimal supervision. Specific Duties & Responsibilities Performance of analyte testing in various biological sample types using MSD and Luminex multiplex formats. Preparation of samples for flow cytometric assays. Flow cytometry sample acquisition. Data interpretation, analysis, and data entry. Maintenance and organization of specimen repository. Maintenance of laboratory supplies and laboratory equipment. Discussion of testing results with laboratory manager, laboratory director, and core facility users. Analysis of data, formulation of conclusions,...

Job Req ID:  108319 We are seeking a Sr. Research Specialist who will utilize their knowledge and skills gained through education and significant research experience. The Sr. Research Specialist will be responsible for conducting behavioral and neurobiological experiments with animal models primarily in studies of aging and neuropsychiatric disorders, maintaining the research facilities, and organizing the various projects within the scope of the laboratory research programs. Specific Duties & Responsibilities Perform all aspects of experiments including, but not limited to, coordinating with members of the various laboratory programs, acquiring animals from collaborators and vendors, maintaining a colony of pathogen free animals, maintaining animal inventories, and monitoring their health status and environment, and maintaining an animal testing facility. Planning and scheduling experiments on various behavioral tasks, where duties related to behavioral...