340 postdoctoral scientist jobs found

Target Discovery Institute, NDM Research Building, Old Road Campus, Heading, Oxford, OX3 7BN We are seeking to appoint a Postdoctoral scientist with experience in protein purification, biophysical characterization of protein ligand interactions, functional assay development as well as crystallization and structure determination of proteins. You will join the CMD Chemical Biology Group at the Target Discovery Institute, Nuffield Department of Medicine. You will be responsible for unravelling the fundamental role of novel RNA binding proteins involved in human disease. You will be developing biochemical assays and studying the interaction of low molecular weight modulators to protein interaction domains and understand the SAR (structure activity relationship) of compound classes with the goal to develop a highly selective first- in-class chemical probes. You will contribute to the scientific output by publishing high quality manuscripts and by representing the group on...

Your tasks and responsibilities: The applicant will join the team of Professor Sebastian Suerbaum at Max von Pettenkofer Institute of LMU Munich. The group uses a combination of genetic, genomic and biochemical approaches to study the population biology, evolution and pathogenesis of gastrointestinal infections with a special focus on the carcinogenic gastric pathogen Helicobacter pylori. Your qualifications: The position is initially limited to two years, with a perspective of prolongation. Applicants must have completed their studies in life sciences with a doctoral degree. Furthermore, we expect applicants to be highly motivated, to have excellent communication and interpersonal skills and to like working in a team. Preference will be given to candidates with documented experimental skills in the area of molecular microbiology and experience in handling pathogenic bacteria. NGS/bioinformatics capabilities are likewise very welcome. Important publications: F. Ailloud...

We have an exciting opportunity for a highly motivated Research Assistant to join Dr Mike Chapman's research group in the MRC Toxicology Unit. Previous work in the lab quantified the cell surface proteome of primary myeloma for the first time. Using this and other data we have identified immunotherapeutic targets and are establishing novel CAR-T and other immunotherapies against myeloma. We are interrogating these therapies using in vitro and in vivo models in order to optimise their efficacy and toxicity profiles. Ultimately, we will progress the most promising of these therapies to clinical trials through links and collaborations with Addenbrooke's Hospital and the Cambridge Cancer Centre Immunology Program. On the back of a highly successful beginning to this project we have received additional funding for a Research Assistant to join our team, to help advance this exciting project and develop novel CAR-T therapies for myeloma treatment. The successful candidate will work...

NTU Main Campus, Singapore Full time R00011071 Lee Kong Chian School of Medicine invites applications for: Research Fellow ( Biochemistry and Structural Biology) in the laboratory of Assoc Prof Luo Dahai A/Prof Luo Dahai’s Lab in the Lee Kong Chian School of Medicine, Nanyang Technological University (https://www.ntu.edu.sg/medicine) is looking for a highly motivated, goal-driven, and team- oriented postdoctoral scientist to join our collaborative team. Research in the lab is focused on understanding fundamental mechanisms of RNA virus replication and host immune response using interdisciplinary approaches ranging from biochemistry, structural biology, virology and cell biology. NTU Institute of Structural Biology (https://www.ntu.edu.sg/nisb) provides an excellent infrastructure for high-resolution cryo-EM/ET, X-ray crystallography, NMR and other biophysical equipment. We offer a dynamic and stimulating work environment for conducting cutting-edge...

A full or part-time working opportunity is available for a Postdoctoral Scientist to join the Mahata laboratory at the Division of Immunology, Department of Pathology, University of Cambridge, in a collaborative research project. The University of Cambridge is a world leader in biological research. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to Cambridge from all over the world, creating a lively international community to exchange ideas to discover and innovate. You will join a pioneering research programme to investigate the underlying principles of immune cell-mediated steroid biosynthesis in regulating cancer immunity. The research area offers an excellent opportunity to create a new dimension in cancer immunology, allowing you to develop your unique research niche and academic independence. You will thrive in a highly collaborative and supportive research environment. You should have a PhD, or due to...

The University of Cambridge wishes to appoint a postdoctoral scientist to join the research groups of Prof Maria Grazia Spillantini and Prof Patrick Chinnery at the Department of Clinical Neurosciences and the MRC Mitochondrial Biology Unit https://spillantinilab.medschl.cam.ac.uk/ http://www.mrc-mbu.cam.ac.uk/people/patrick-chinnery. The position is part of a collaborative Wellcome Trust award, lead by Prof Nick Jones (https://www.imperial.ac.uk/people/nick.jones/publications.html ) at the Department of Mathematics at Imperial College, London. The award aims to understand the role of cryptic mitochondrial DNA (mtDNA) mutations in aging and neurodegenerative disease. You will be based at the Clifford Allbutt Building in the Department of Clinical Neurosciences at the University of Cambridge and will have strong links also with Imperial College London, with regular travel between the two sites throughout the tenure. You will be involved in generating and...

JOB OPENING ID 228731 WORKING TITLE Research Fellow JOB TITLE RESEARCH FELLOW WORK LOCATION Ann Arbor Campus Ann Arbor, MI FULL/PART TIME Full-Time REGULAR/TEMPORARY Regular FLSA STATUS Exempt ORGANIZATIONAL GROUP Medical School DEPARTMENT MM Pharmacology Department POSTING BEGIN/END DATE 1/04/2023 - 2/28/2023 CAREER INTEREST Research Fellows Summary A unique postdoctoral scientist opportunity is available within the Department of Pharmacology at the University of Michigan Medical School.  This dually mentored position will operate at the interface of basic science in G protein coupled receptor signaling and translational hematology.  You should have knowledge or prior training in biochemistry, pharmacology, cell or molecular biology and have the desire for a diverse training experience.  It is expected that the postdoctoral scientist will perform the following activities semi-independently under the...

Description Seeking Expression of Interest from junior scientists with expertise in physical oceanography, data-driven methods, and high-resolution numerical modeling. This opportunity is for a postdoctoral position at New York University, supervised by Shafer Smith (Professor of Mathematics and Atmosphere Ocean Science at the Courant Institute).   The postdoc will join a small multi-institutional team that includes Ryan Abernathey (professor of Earth And Environmental Science at Columbia University), Spencer Jones (professor of Oceanography at Texas A&M University), and Dhruv Balwada (research scientist at the Lamont-Doherty Earth Observatory), conducting research as part of the NASA Surface Water and Ocean Topography (SWOT) Science Team.  The SWOT mission, launching in December 2022, will provide new swath-based altimetric observations of sea surface height. The overall goal of our project is to develop new data-driven methods, leveraging...

DEPARTMENT/LOCATION Wellcome Trust/Cancer Research UK Gurdon Institute SALARY £34,308 - £42,155 REFERENCE PR34627 CATEGORY Research PUBLISHED 12 December 2022 CLOSING DATE 6 February 2023 We are looking for a talented and motivated postdoctoral scientist to join the lab of Dr Emma Rawlins. The Rawlins lab studies lung development and lung stem cells with a particular focus on using human organoid models to study cellular and molecular mechanisms controlling development and repair. We have recently developed a series of innovative human lung organoid models and accompanying CRISPR tools which will further enable the study of human lung disease. This position is part of a Wellcome-funded highly collaborative UK-based project which brings together human geneticists, lung cell biologists and clinicians to define the genetics and cell biology underlying chronic human lung disease. The specific project will focus initially on the use of...

Description Research position at the level of Postdoctoral Research Scientist is available at the Center for Radiological Research (CRR.columbia.edu) at Columbia University Irving Medical Center in New York to investigate the effect of acute high-dose radiation exposure on the gut microbiome and its impact on gastrointestinal (GI) tract injury. We have developed an orally administered radiomitigator that is specifically targeted to the mucosal surface of the GI tract to potentially alleviate the deleterious effects of radiation in animal models. The major focus of this research study will be to perform longitudinal structural and functional studies to determine the impact of radiation, on GI architectural integrity, commensal gut microbiota composition and diversity, and microbiome-host interactions after drug treatment/irradiation using conventional and human gnotobiotic mouse models, flow cytometry, and ELISA-based assays. Additionally, mechanistic studies will be performed...

Description The Center for Climate Systems Research at Columbia University (https://ccsr.columbia.edu/) invites applicants for a Postdoctoral Research Scientist position in cloud physics, global atmospheric modeling, and satellite observations at its Morningside campus in New York City. Appointment is full-time and made annually and is contingent upon funding and performance.   Of all climate feedbacks on decadal to centennial scales, the most uncertain are those associated with changes in clouds, in both the current and previous Coupled Model Intercomparison Project (CMIP) generations. Such diverse behavior limits confidence in projections of future climate. The project’s research goals are to characterize the response of different cloud types to climate variations (cloud feedbacks) using active-sensor CALIPSO-CloudSat observations in conjunction with other A-Train observations, and to develop constraints for climate sensitivity and climate model...

Description Dr. Suzanne Leal's group in the Center for Statistical Genetics at Columbia University Department of Neurology is looking for a qualified candidate for  Postdoctoral research scientist  positions. The candidate is expected to work on one or more of the following concentrations: Developing statistical methods to analyze complex traits, e.g. approaches to detect pleiotropy and interactions using sequence, imputed, family and population-based data. Developing statistical and computational methods for family and population based genetic association studies. Analyzing complex traits e.g. late-onset Alzheimer’s disease, age-related hearing impairment, tinnitus, lipids, asthma, type 2 diabetes, and obesity. It includes but not limited to data annotation, quality control, and analysis of sequence, microarray, imputed genotype data, and copy number variations. Qualifications Applicants should have a Ph.D. or related...

Department of Physiology, Anatomy & Genetics, Sherrington Building, Parks Road, Oxford, OX1 3PT Postdoctoral Research Scientist Full time, Fixed term post until 23rd May 2026 Grade 7: £34,308 - £42,155 per annum This is an exciting opportunity for a Postdoctoral Research Scientist to join the Lakhal-Littleton lab and contribute to our research. Reporting to Prof Lakhal-Littleton, the successful as a member of a research group will be responsible for carrying out research to understand the role of cardiac hepcidin/ferroportin axis in the management of iron deficiency in heart failure. The post holder will provide guidance to less experienced members of the research group, including postdocs, research assistants, technicians, as well as PhD and project students. The researcher will be managing the role of hepcidin in heart failure project, carrying out experiments independently and contributing to data analysis and interpretation. They will also...

Description The Lamont-Doherty Earth Observatory (LDEO) of Columbia University located in Palisades, New York, invites applications for a Postdoctoral Research Scientist position in tropical physical oceanography and climate dynamics. The research project will study the response of the upper tropical Pacific Ocean to rising greenhouse gases. It will focus on the historical period where there is a discrepancy between the observed trends in tropical Pacific sea surface temperatures and upper ocean thermal structure and those simulated by state-of-the-art coupled climate models. The work will involve analysis of surface observations and ocean re-analyses and coupled model simulations and conducting suites of simulations with forced ocean models. Analysis tools will include novel approaches from artificial intelligence and machine learning. The aim is to elucidate the dynamical and thermodynamical processes that govern how the tropical Pacific upper ocean responds to rising...

Description The Department of Anesthesiology at Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, seeks a Postdoctoral Research Scientist to investigate the mitochondrial mechanisms of propofol toxicity. Experiments involve wild-type and genetically modified mice using  in vitro  and ex-vivo Langendorff models. Proficiency in animal husbandry, tissue collection, mitochondrial isolation, enzyme activity assays, immunohistochemistry, western blotting, light and fluorescence microscopy are required. Ability to work with minimal guidance is expected. The desired candidate must be able to develop and learn new techniques as required for these studies as well as teach techniques to other members of the laboratory. Additional duties may be assigned as required by the PI. Qualified applicants must be a recent recipient of a PhD or MD awarded within the past three years. The university offers a competitive salary and an excellent...

Description Two Postdoctoral Research Scientist positions are available immediately for highly motivated candidates to join the Amundson Laboratory, which is part of the Center for Radiological Research (crr.columbia.edu) in the Department of Radiation Oncology at Irving Medical Center in Upper Manhattan. Two major NIH-funded project areas are available. The first uses gene-expression-based approaches to understand and predict individual responses after exposures to radiation. The second project is focused on exciting approaches for curing hard-to-treat cancers using new types of particle radiotherapy. The projects involve collaborations with the unique facilities at Columbia’s Mouse Hospital (www.olivelab.org) and Columbia’s Radiological Research Accelerator Facility (www.raraf.org). This is an outstanding opportunity to work with investigators in leading radiation biology and pancreatic cancer laboratories. Successful candidates must have experience in...

Description This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Postdoctoral Research Scientist is an exciting one. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. KEY RESPONSIBILITIES Children’s Health Redox Center (CHRC), NY, USA is seeking a hard-working and enthusiastic individual to join a multidisciplinary program focused on multi-omics, particularly lipidomics and redox lipidomics, and mass spectrometry-based spatial biology. Candidates with a background in chemistry, cell/redox biology and PhD in any of the following fields are invited to apply: lipidomics, metabolomics, proteomics, bioinformatics, systems biology or computational biology. Current research interests of the CHRC include development and application of multiplex omics approaches and advanced data...

Description The Data Science Institute (DSI) at Columbia University invites applications for the position of a Postdoctoral Research Scientist working with the Natural Language Processing Group.  DSI strives to be a force for change. We advance the state-of-the-art in data science; transform all fields, professions, and sectors through the application of data science; and ensure the responsible use of data to benefit society. Drawing on Columbia’s strengths in computer science, statistics, and industrial engineering and operations research, DSI was launched in 2012 to unite our expertise and a University-wide interest in this revolutionary approach. The University is a trailblazer in the field and is uniquely poised to expand data science to every corner of the institution. We train the next generation of data scientists, develop innovative technology, foster collaborations in advancing techniques to interpret data and address pressing societal problems,...

Description The Department of Epidemiology at Columbia University Mailman School of Public Health in New York City invites applications for a Postdoctoral Research Scientist with interest in causal inference methods, drug use disorders, and pharmacoepidemiology.  The fellow will join a causal inference research team in uniting design and analytic strategies to bridge medication for opioid use disorder (MOUD) trial evidence to real-world target populations by: 1) empirically identifying those individuals not represented or under-represented in MOUD trials, and 2) accurately and reliably generalizing expected MOUD effects on treatment retention to the adult Medicaid population, with the broad goal of optimizing the generalizability and policy-relevance of future clinical trials.  Depending on their research interests, there are also opportunities to participate in other ongoing research projects; these include 1) identifying heterogeneous treatment effects in MOUD...

Description Columbia University’s Mortimer B. Zuckerman Mind Brain Behavior Institute brings together world-class scientists across academic disciplines conducting pioneering research to transform our understanding of how the brain works – and gives rise to mind and behavior. The Institute fosters a collaborative and inclusive environment across 50+ labs, advancing insights into human health by exploring how the brain develops, performs, endures, and recovers. At the Zuckerman Institute, we are committed to becoming a more inclusive, equitable, and diverse place of scientific discovery and support a culture of respect. Promoting diversity in science will help drive the transformative science that can change the world.  Situated in the Jerome L. Greene Science Center on Columbia’s Manhattanville campus, the state-of-the-art building offers an environment where the highest level of scholarly scientific research takes place on a daily basis, with the...