39 faculty science biology jobs found in Oxford

RDM Division of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, OX3 9DU *This is a re-advertisement, previous applicants need not apply. We are seeking a highly motivated Postdoctoral Research Assistant to come and work under the overall supervision of Prof. Keith Channon, in the Division of Cardiovascular Medicine’s laboratories at the Wellcome Centre for Human Genetics (www.well.ox.ac.uk), working closely with the laboratory of Prof. Chris O’Callaghan in the same building. The Wellcome Centre for Human Genetics is a world class molecular medicine research facility located on the University of Oxford’s Old Road campus, co-located with major research institutes, facilities and hospitals. This facility provides an outstanding work environment, with excellent core services and opportunities for interactions with cardiovascular, molecular and developmental biologists & geneticists. You will work in a team with students, research assistants and...

Department of Biochemistry, DCHB, South Parks Road, Oxford, OX1 3QU We are seeking to appoint a Postdoctoral Research Associate to join the lab of Dr Clinton Lau, studying how the malaria parasite cytoskeleton organises the cell. You will identify and characterise proteins that bind to the cytoskeleton of Plasmodium falciparum. Our research projects require a creative, multidisciplinary approach, and as such provide opportunities across structural biology, biochemistry and cell biology including single molecule fluorescent microscopy and cryo electron microscopy. You will join an enthusiastic lab in the Department of Biochemistry. We have access to excellent facilities such as the Central Oxford Structural and Molecular Imaging centre (COSMIC), as well as the Micron imaging facility. In addition, we have a strong focus on career development, with training and mentoring available. You should hold a PhD/DPhil together with relevant experience in a field such as structural...

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY. We are looking a talented Postdoctoral Research Assistant to join the group of Associate Professor Tal Arnon at the Kennedy Institute, the University of Oxford. The project will explore molecular and dynamic mechanisms that regulate humoral immunity in the lung with emphasis on the roles of resident memory B cells in this process. An important advance from the past decade has been the recognition that adaptive immune cells are not only capable of remembering the antigens they encountered but also the specific sites in which these encounters occurred, such that tissues that are susceptible for infection are reinforced with protective clones. This type of localized immunity proved highly effective in the case of resident memory T cells, leading to accelerated pathogen clearance and reduced widespread of infection in...

Target Discovery Institute, NDM Research Building, Old Road Campus, Heading, Oxford, OX3 7BN We are seeking to appoint a Postdoctoral scientist with experience in protein purification, biophysical characterization of protein ligand interactions, functional assay development as well as crystallization and structure determination of proteins. You will join the CMD Chemical Biology Group at the Target Discovery Institute, Nuffield Department of Medicine. You will be responsible for unravelling the fundamental role of novel RNA binding proteins involved in human disease. You will be developing biochemical assays and studying the interaction of low molecular weight modulators to protein interaction domains and understand the SAR (structure activity relationship) of compound classes with the goal to develop a highly selective first- in-class chemical probes. You will contribute to the scientific output by publishing high quality manuscripts and by representing the group on...

Division of Structural Biology, Henry Wellcome Building of Genomic Medicine, Roosevelt Drive, Old Road Campus, Headington, Oxford, OX3 7BN We are seeking an ambitious and highly motivated Postdoctoral Research Scientist to join the research Group of Professor Jonathan Grimes, located in the Division for Structural Biology, at the Nuffield Department of Medicine. You join a Wellcome Trust-Funded Project to understand in molecular detail Influenza virus replication and transcription, and the process of viral assembly. You will be responsible for managing your own academic research activities, which involves small scale project management to co-ordinate multiple aspects of work and meet deadlines. You will adapt existing and develop new scientific techniques and experimental protocols, and test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will contribute ideas for new research projects, and...

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY. The Kennedy Institute has an exciting oppourtunity for a highly motivated post-doc to join a strong interdisciplinary team investigating the roles of fibroblasts in rheumatoid arthritis under the leadership of Professor Chris Buckley. The team has an opening for a talented computational reseacher to join the group of Associate Professor Stephen Sansom and lead bioinformatic investigations of the cellular basis of disease initiation, development and resolution. This research will take advantage of rich single-cell and spatial transcriptomics datasets from patient cohorts and animal models. Novel findings will be prioritised, validated and tested in close partnership with wet-lab colleagues. The ultimate goal of the project is to understand the roles of different fibroblast subtypes with a view to informing selective...

Applications are invited for a 3-year postdoctoral research position within the Drug Transport and Tumour Metabolism Lab, led by Dr Louise Fets. We are seeking a talented scientist to deliver an exciting and innovative research project funded by a 6-year Cancer Research UK-funded Career Establishment Award on “Understanding how membrane transporters influence variability in cancer drug uptake and investigating implications for efficacy”.... Job listing information Reference MED03624 Date posted 24 January 2023 Closing date 21 February 2023 Job summary Applications are invited for a 3-year postdoctoral research position within the Drug Transport and Tumour Metabolism Lab, led by Dr Louise Fets. We are seeking a talented scientist to deliver an exciting and innovative research project funded by a 6-year Cancer Research UK-funded Career Establishment Award on “Understanding how membrane transporters influence...

The GEMMA Project GEMMA, which stands for Genome, Environment, Microbiome and Metabolome in Autism, is a multicentre European Commission Project for exploring interactions between gut microbiome, metabolome, epigenome and immune function in order to discover new biomarkers useful for early diagnosis of autism, which would pave the way for early intervention. The European Commission has selected and financed GEMMA project as part of its Horizon... Job listing information Reference MED03611 Date posted 10 January 2023 Closing date 31 January 2023 Job summary The GEMMA Project GEMMA, which stands for Genome, Environment, Microbiome and Metabolome in Autism, is a multicentre European Commission Project for exploring interactions between gut microbiome, metabolome, epigenome and immune function in order to discover new biomarkers useful for early diagnosis of autism, which would pave the way for early intervention. The...

Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Headington, Oxford, OX3 9DU Contract type: Fixed term for 12 months Hours: Full-time About the role You will work on a new, translational project, funded by the MRC Confidence in Concept fund and industry partner, Oxford Biomedica, to generate antigen-specific, human regulatory B cells (Breg). You will be responsible for the development and implementation of lentiviral platforms and CRISPR/Cas9 techniques to deliver genes encoding B cell receptor constructs to primary human B cells. Successful realisation of this project will demonstrate proof of concept design of precision B cell therapies in transplantation and immune-mediated disorders. You will be based within the Nuffield Department of Surgical Sciences in the John Radcliffe Hospital, as your normal place of work This position offers a unique opportunity to contribute to the work of an internationally recognised team of scientists and...

Department of Biochemistry in association with Trinity College The Department of Biochemistry is seeking to recruit an Associate Professor whose research addresses fundamental questions in the broad area of molecular & cellular biology. Researchers with an interest in the processes of transcription and gene regulation in either prokaryotes or eukaryotes are strongly encouraged to apply. In addition to your research, you will contribute to teaching the next generation of Biochemists through our 4-year Masters-level degree course in Molecular and Cellular Biochemistry.  You will be a Tutorial Fellow of Trinity College. You will join one of our highly interactive interdisciplinary research themes applying biochemical, biophysical and computational approaches to major questions in cell & developmental biology, human health and infectious disease processes. High quality laboratory & office space will be provided in the newly completed Dorothy Crowfoot Hodgkin...

11a Mansfield Road, Oxford, OX1 3SZ This is a exciting opportunity to join the Agile Initiative and Jackson Aquatic Ecology Lab as a Postdoctoral Plankton Ecologist to provide rapid evidence-based solutions to the needs of environmental policy-makers. The post-holder will conduct a piece of intensive research (called a “sprint”) from 1st April 2022 for 1 year. This will involve working within an interdisciplinary team of researchers based in the Department’s of Biology (Michelle Jackson) and Earth Sciences (Heather Bouman, Ros Rickaby, Mike Kendall, Joe Cartwright). The successful candidate will hold a PhD in a relevant area of plankton ecology and have experience in working with plankton cultures in the laboratory. They will also have field work experience, a excellent understanding of multiple stressor theory, and enthusiasm for advancing our understanding of the ‘Blue Carbon’ stored in pelagic communities. While being an independent...

Department of Chemistry, Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA Applications are invited for a Postdoctoral Research Associate to work on a research project entitled “Small molecule modulation of metabolic function and new target discovery in human cellular models”, working under the supervision of Professor Angela Russell for a period of up to 24 months. This project is funded by Novo Nordisk and is carried out in close collaboration with scientists at Novo Nordisk Research Centre Oxford (NNRCO). This is an exciting opportunity to work in an industry-academia collaboration with world leading researchers and contribute to the development of innovative new therapeutic approaches for metabolic disorders, an area of significant unmet medical need.  Find out more about the Russell group’s research at: russell group   Applicants must hold a PhD in Organic Chemistry, Medicinal Chemistry or Chemical Biology or a related...

Ludwig Institute for Cancer Research, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ We are seeking to appoint a Senior Postdoctoral Research Scientist to join the Ludwig Institute for Cancer Research. You will participate in the Ludwig Cancer Research funded research programme led by Prof Skirmantas Kriaucionis, Dr Benjamin Schuster-Böckler, Prof Chunxiao Song, Prof Xin Lu, and provide statistical analysis plans for studies while contributing to the overall planning of studies. You will be responsible for advising laboratory and other bio-statistical staff working on relevant projects, and assisting others in their work where appropriate. You will conduct detailed analysis of datasets, as well as develop and tailor methodologies for analysis and data collection in collaboration with members of the research team. It is essential that you hold a PhD in Biostatistics, Mathematics, Statistics, Computing, Mathematical Biology or a related subject....

DCHB, South Parks Road, Oxford, OX1 3QU THIS IS A RE-ADVERTSEMENT AND PREVIOUS APPLICANTS SHOULD NOT RE-APPLY We are seeking to appoint a Postdoctoral Research Associate to join the lab of Prof Peter Sarkies to spearhead a project to use computational analyses of gene networks in order to identify potential novel sources of DNA damage, focussing on metabolic and epigenetic pathways.  Two approaches will be followed: coevolution across species to identify modules of proteins that co-occur across evolution, and co-expression across both healthy tissues and cancer to identify proteins that share similar (or antagonistic) expression profiles across multiple human samples.  Pairs of proteins that are predicted to co-evolve will be tested further using analysis of mutation signatures in cancer.  This is an excellent opportunity for a computational biologist to develop their skills in analysis of “big data”, as well as to further our understanding of the...

Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ About the role We have an exciting opportunity to join the Department of Oncology as a Teaching Fellow. You will play an important role primarily providing educational leadership to academic staff involved in the delivery of our new MSc in Applied Cancer Science, which launches in October 2023. You will work alongside the Course Director to develop the course content including lectures, tutorials, and laboratory practical teaching. You will oversee the operational management of the course and be a key point of contact for students. For this role we are looking for someone with a doctoral level qualification in a relevant area, or an MSc and significant relevant industry experience, to be able to guide students in developing industry-relevant practical skills. The ideal candidate will have experience in teaching in a higher education setting, including programme or...

Department of Chemistry, 12 Mansfield Road, Oxford, OX1 3TA and Department of Pharmacology, Mansfield Road, Oxford, OX1 3QT Applications are invited for a Postdoctoral Research Associate to work on a research project entitled “Degrader compounds for the oncogenic transcription factor LMO2”, working under the supervision of Professor Angela Russell for a period of 18 months. This project is funded by Cancer Research UK and is carried out in close collaboration with the groups of Professor Terry Rabbitts (Institute for Cancer Research) and Dr Andrew Turnbull (Cancer Research Horizons Therapeutic Innovation). This is an exciting opportunity to work in a multidisciplinary collaboration with world leading researchers and contribute to the development of an innovative new therapeutic approach for T-ALL, an area of significant unmet medical need. Find out more about the Russell group’s research at: russell group/ Applicants must hold a PhD in Organic...

Department of Oncology, Weatherall Institute for Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS/Old Road Campus Research Building, Headington, Oxford OX3 7DQ About the role An opportunity has arisen for a Postdoctoral Researcher to join Sir Walter Bodmer’s research group working on the genetics, cell biology and differentiation of colorectal cancer, with a special interest in the development of novel immunological therapies. Your main role will be to develop and carry out preclinical testing of bispecific monoclonal antibodies targeted against tumour determinants as well as T lymphocyte engaging surface markers. This will involve the use of the laboratory’s extensive collection of more than 120, mostly fully characterised, colorectal cancer (CRC) derived cell lines as well as CRC organoids derived from freshly obtained CRC biopsies. You will also be expected to help in other projects on aspects of the control of differentiation and...

Department of Chemistry, Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA and Department of Pharmacology, Mansfield Road, OX1 3QT Applications are invited for a Postdoctoral Research Associate to work on a research project entitled “Second generation arylhydrocarbon receptor antagonist, utrophin modulators for the treatment of Duchenne muscular dystrophy”, working under the supervision of Professor Angela Russell for a period of 24 months. This project is funded by the MRC and is carried out in close collaboration with the groups of Professor Dame Kay Davies (Physiology, Anatomy and Genetics) and Professor Matthew Wood (Paediatrics), and the Oxford-Harrington Rare Disease Centre. This is an exciting opportunity to work on a collaborative project with world leading researchers and make a real impact to the development of a new therapeutic approach for the rare neuromuscular disease, Duchenne muscular dystrophy, a disease with significant unmet...

Department of Biochemistry in association with Worcester College The Department of Biochemistry is seeking to recruit an Associate Professor whose research uses biochemistry and biotechnology approaches to address fundamental questions in the broad area of molecular & cellular biology. Researchers applying chemical biology approaches in either prokaryotes or eukaryotes are strongly encouraged to apply. In addition to their research, the appointee will contribute to teaching the next generation of Biochemists through our 4-year Masters-level degree course in Molecular and Cellular Biochemistry and by acting as a Tutorial Fellow at Worcester College. The appointee will join one of our highly interactive interdisciplinary research themes applying biochemical, biophysical and computational approaches to major questions in cell & developmental biology, human health and infectious disease processes. High quality laboratory & office space will be provided in the newly...

Centre for Medicines Discovery, BioChemistry Phase II, South Parks Road, Oxford, OX1 3QU We are seeking to appoint a highly motivated Postdoctoral Researcher with experience in protein crystallography to join the Alzheimer’s Research UK Oxford Drug Discovery Institute, where you will be part of a larger team carrying out research into new dementia targets at Centre for Medicines Discovery. Reporting to the Assay Development and Screening Team Leader (Dr Emma Murphy), you will become an integral part of target-based project teams working on drug discovery projects and employ cutting-edge structural and biophysical/biochemical research to characterise new proteins and carry out mechanism of action studies. You will be responsible for performing fragment screening experiments on targets involved in Alzheimer’s disease and other neurodegenerative diseases causing dementia and be expected to take the lead in advancing initial fragment hits to potent compounds by...