LMU Munich (Ludwig-Maximilians-Universität München)
Ludwig Maximilian University of Munich, Geschwister-Scholl-Platz, Munich, Germany
Your tasks and responsibilities:
In the proposed project we aim to use P2X7 knock-out and BAC transgenic P2X7-EGFP mouse models (Kaczmarek-Hájek, Zhang, Kopp et al., eLife, 2018) in combination with biochemical (cross-linking mass spectrometry), biophysical (two-electrode voltage clamp, voltage clamp fluorometry) and functional approaches (migration assays, fluorescence imaging) to identify and validate identified P2X7 interaction partners and possible roles of P2X7 cell migration.
Your qualifications:
Outstanding MSc degree in the area of biomedicine, biochemistry, biology, pharmacy or similar
We are looking for highly motivated researchers with enthusiasm for basic science
You should have a good background in molecular biology and biochemistry
Ability to responsibly plan and perform experiments and to work in an international team
Experience in working with genetically modified mice, functional analysis of in channels and cell migration assays...