Stanford University
Stanford, CA, USA
The Division of Infectious Diseases and Geographic Medicine, within Stanford University, Department of Medicine is seeking a Life Science Research Professional II to perform more complex functions and activities involved in defined research projects, and independently conduct a portion of the research project(s).
Studies in our lab are driven by the hypothesis that IgG repertoire diversity is a central driver of heterogeneity in human immune functioning and susceptibility to diseases. We are specifically interested in diversity that exists in the Fc domain repertoire among people, which we define by serum IgG subclass and Fc glycoform distributions. We have found that the Fc domain repertoire of an individual impacts key immune processes such as vaccine responses and susceptibility to antibody-dependent enhancement of dengue disease (Wang TT, Cell. 2015 and Wang TT, Science. 2017). This is because IgG subclasses and Fc glycoforms dictate the structure of Fc domains...