131 faculty medicine jobs found in Cambridge

Applications are invited for two Senior Research Associates (Junior Group Leaders)) to join The Early Cancer Institute at the University of Cambridge (https://www.earlycancer.cam.ac.uk/), a world-leading centre for research and the UK's only institute dedicated to Early Cancer. The Junior Group Leader(s) will initiate and build an independent research programme related to one or more of the aims (risk prediction, detection, interception) of the Early Cancer Institute. Work related to a cancer of unmet need such as pancreas, or work to augment our emerging interest in immunophenotyping or data science including AI/machine learning is especially encouraged. Applicants should have a PhD in a subject relevant to early detection of cancer with post-doctoral research experience and an excellent academic record and peer-reviewed publications that have had impact in the field. Relevant disciplines include cell and molecular biology, computational biology, physical sciences or other STEM...

We wish to appoint a grant writer for two years in the first instance to write funding proposals relating to research in autism in priority areas (including diagnosis, early intervention, support in employment, suicide prevention, special educational needs, and the criminal justice system). The post is funded by the charity the Autism Centre of Excellence (ACE) at Cambridge whose mission is to fund excellent autism research and translate this into excellent support services for autistic people and their families. The postholder will lead the development, writing, and submission of grant proposals falling within ACE's key priority areas (listed above). They will report to the Director of Cambridge University's Autism Research Centre (ARC) (Professor Simon Baron-Cohen) and the ARC Director of Strategy (Dr Carrie Allison) and ensure alignment with the ARC's overall mission, which is to understand the causes of autism and improve the health and well-being of autistic people and...

The Markowetz lab at the Cancer Research UK Cambridge Institute is looking for a postdoctoral researcher to work on the genomics of chromosomal instability. This is an opportunity for an ambitious scientist to lead the development of computational methods to understand the causes of chromosomal instability and best ways to exploit them, and to closely interact with experimentalists in the lab in an iterative computational-experimental cycle. The project is an extension of the copy number signatures developed in Drews et al, Nature (2022) and funded by an ERC Advanced Grant. The Markowetz lab is a mixed computational/experimental lab with a strong track record in machine learning working on a broad range of topics in cancer genomics and imaging. It offers a supportive and diverse environment (see: Markowetz, 'You are not working for me, I am working with you', PLoS Comp Bio 2015) and has been a jumping board for many successful careers in academia, industry, and spin-out...

Applications are invited for a Research Associate to join the group of Dr Matt Hoare within the new Early Cancer Institute at the Cambridge Biomedical Campus. Our group is interested in why patients with chronic liver disease develop liver cancer (hoarelab.uk). This is an exciting opportunity to join a 5-year CRUK-funded project, based on previous findings from the group (Brunner et al, Nature, 2019; Ng et al, Nature, 2021) and will further define how acquired somatic mutations impact on liver disease progression, cancer risk and systemic metabolic dysfunction. We are seeking to hire a motivated post-doctoral Research Associate to join the team. The successful candidate will join a pioneering research project, working in close collaboration with the Rosenfeld group (http://www.rosenfeldlab.org/) at the neighbouring CRUK Cambridge Institute, developing novel assays to identify liver-derived mutant DNA in circulating blood. To deliver this project the successful candidate will...

Applications are invited for a post-doctoral position in the group of Dr Janin Lautenschläger at the Cambridge Institute for Medical Research (CIMR, Biomedical Campus, University of Cambridge). Our lab studies the function of alpha-synuclein, a synaptic protein involved in Parkinson's disease. We have shown that alpha-synuclein undergoes protein phase separation and are now aiming to understand how alpha-synuclein phase separation is regulated and which functional role this plays in synaptic transmission. The successful candidate would have a strong interest in molecular mechanisms of neurodegeneration and experience with iPSC-derived neuronal cultures including viral transgene expression and CRISPR/Cas9 gene editing. In addition, experience in molecular biology (i.e. molecular cloning, Western blot) and in microscopy are essential. Experience in advanced imaging i.e. FRAP, ratiometric dyes like Synapto-pHluorin, Airyscan, SIM and/or FLIM would be beneficial. We will be...

The University of Cambridge is seeking to appoint a full time Teaching Associate in Hebrew and Aramaic within the Hebrew studies section of the Department of Middle Eastern Studies. Key activities associated with the role include: Teaching Classical Hebrew and pre-modern Aramaic at undergraduate and graduate level. Supervising undergraduates and Mphil. students. Assessment and examining. Participate in institution's meetings and undertake some administrative duties, as commensurate with the grade of the role. Student recruitment and admissions Applicants must have: PhD in the field of Hebrew, or equivalent demonstrable experience and/or a teaching qualification as appropriate. Ability to teach Classical Hebrew and pre-modern Aramaic. Preferably also knowledge of Modern Hebrew. Preferably some experience of successfully developing and delivering teaching at university level. Excellent interpersonal and communication skills. The...

Applications are invited for an enthusiastic and committed post-doctoral scientist to join a vibrant team investigating the cell biology of a group of neurological conditions called hereditary spastic paraplegias. This project is based in the group of Professor Evan Reid at Cambridge Institute for Medical Research and is funded for 3 years. It would be particularly appealing for a cell biologist who is interested in understanding the causes of genetic disease. The project aims to understand the functions of hereditary spastic paraplegia proteins in the molecular pathogenesis of axonal degeneration. The work will be at the interface between cell biology (especially membrane traffic) and molecular neuroscience, and will begin with functional genomic synthetic lethality screens using human iPSC-derived neuronal models of HSP, before going on to characterize the cell biology of "hits" from the screen. The lab employs an integrated approach that combines state of the art cell...

The role holder will work on EU grants in the Marks group and support the scientific components on whole genome sequencing of bacterial isolates. This will include coordinating the collaboration with overseas partners in sub-Saharan Africa, the daily follow-up of sample management, facilitating communication among the international partners and cross-functional teams and partnering institutes. Additionally, the Research Assistant is expected to perform analyses on whole genome sequence data of bacterial isolates obtained within the studies. This position offers an ideal opportunity for a highly motivated research assistant wishing to advance their career in microbiology surveillance and whole genome sequencing. This 100% role will be based in the Department of Medicine, University of Cambridge and the successful candidate will be required to travel to research sites in Africa and elsewhere (25% of time is expected to be spent out of the country). Fixed-term: The...

Applications are invited for a Clinical Lecturer in Anaesthesia, Department of Medicine. This post offers unrivalled opportunity to undertake high quality research within an outstanding academic and clinical environment. Applicants should be medically qualified, have full GMC registration, and an existing NTN/NTN(A) in Anaesthesia. You are required to hold or have submitted a PhD/DPhil/MD at the time of your application, and be of the standing required for an appropriate honorary contract of service with the NHS LETB (specialist trainee/LETB). Candidates who have not submitted their PhD/MD at the time of application will not be considered. The offer will be subject to the confirmation of the PhD/MD before commencement in post. This is a fixed term appointment for a maximum of 4 years or until you obtain CCT (subject to any extension that you may apply for and be granted by Health Education England, which can be for a maximum of 12 months). Salary Scales  StR...

Applications are invited for this new post to provide senior leadership in the Medical Informatics for children and young people (CYP) in the Department of Psychiatry. Medical Informatics (CYP)'s research aims to develop personalised medicine approaches that draw on combined administrative datasets to prevention and intervention for mental health conditions in this population. This is a post supported by Cambridgeshire & Peterborough NHS Foundation Trust (CPFT), the Anna Freud Centre and the Cambridge BRC (NIHR BioResource and Paediatric themes). The post holder would be expected to spend one day a week undertaking clinical duties in CAMHS Liaison for CPFT, one day a week working for the Young People's BioResource and three days a week research in informatics in the Department of Psychiatry with the Charm research group. We are looking for candidates who are credible as future independent research leaders, capable of raising grant income as principal applicants to...

The Leverhulme Centre for the Future of Intelligence (CFI) at the University of Cambridge is appointing an Associate Teaching Professor (0.5 FTE). This is a new post, and the appointee will play a key role in the development of the Centre as Associate Director for Education at CFI. The appointment will be for 3 years in the first instance. Leverhulme CFI is a highly interdisciplinary research centre addressing the challenges and opportunities posed by artificial intelligence (AI). Funded by the Leverhulme Trust, CFI is based at the University of Cambridge, with partners in the University of Oxford, Imperial College, and UC Berkeley. This role is an exciting opportunity for a talented individual to make a major contribution to the development of this important new field of study. The purpose of this role is to direct CFI's expanding teaching programmes to ensure they maintain the highest international levels of excellence. This includes overseeing the existing MSt programme...

We invite applications for a postdoctoral Research Associate to work in the Department of Oncology at the University of Cambridge. The successful candidate will also become a member of the Mark Foundation Institute for Integrated Cancer Medicine and the Cancer Research UK Cambridge Centre. This role is an exceptional opportunity to join a strong and passionate interdisciplinary team to develop new deep learning approaches to model the multi-scale spatial evolution of ovarian cancer. The successful candidate will drive the development and application of computational pathology methods to quantify tumour heterogeneity across multiple locations and time points. They will also create frameworks to discover and model spatial correlations with other data modalities such as genomics, transcriptomics, and radiological imaging. The research will aim to reveal new scientific insights into the disease as well as to provide support to critical, unsolved clinical questions. The Research...

We invite applications for a postdoctoral Research Associate to work in the Department of Oncology at the University of Cambridge. The successful candidate will also become a member of the Mark Foundation Institute for Integrated Cancer Medicine, the Cancer Research UK Cambridge Centre, and the Cambridge-GE HealthCare AI partnership. This role is an exceptional opportunity to join a strong and passionate interdisciplinary team to develop new deep learning approaches to model the spatial and temporal response to therapy of ovarian cancer using imaging data. The successful candidate will have access to extensive annotated datasets and drive the development and application of new deep learning approaches to track the evolution of primary and metastatic lesions during treatment. The research will aim to reveal new scientific insights into the disease as well as to provide support to critical, unsolved clinical questions. The Research Associate will be supervised by Dr Mireia...

We are seeking an enthusiastic, motivated individual for a position in the group of Prof. Mike Weekes, in Cambridge Institute for Medical Research at the Cambridge Biomedical Campus. You will join an exciting research programme aiming to identify novel therapeutic targets against human cytomegalovirus (HCMV). This post will involve the use of cutting edge proteomic, structural and biochemical techniques to characterise interactions between HCMV and degraded antiviral restriction factors, determine how these influence viral replication and how this might be prevented therapeutically. This position is available for immediate appointment. Candidates must either have a PhD in a relevant biological subject, or be writing a PhD thesis. Candidates must also have demonstrable expertise in virology, cell biology, structural biology and/or molecular biology. Additional training in proteomics will be provided. Relevant post-doctoral experience is desirable. High quality...

Applications are invited to recruit an enthusiastic post-doctoral scientist to work on an Wellcome funded project in the group of Prof James Nathan. We employ an integrated approach, using biochemistry, cell biology, and CRISPR/Cas9 mutagenesis screens, to understand how oxygen sensing pathways interact with chromatin. The project will focus on the role of hypoxia inducible factors control gene expression, focusing on the histone methyltransferase SET1B (see Ortmann et al Nature Genetics 2021). The work will be pursued in the Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID). This new building provides an exceptional and stimulating environment that promotes collaborative and interdisciplinary research, with state-of-the-art facilities, and is housed on the Cambridge Biomedical Campus alongside the Cambridge Stem Cell Institute. Recent publications related to our approaches and this project include: Ortmann et al. (2021) Nature Genetics (PMID:...

Applications are invited for a post-doctoral Research Associate to join the group of Dr Matt Hoare within the new Early Cancer Institute on the Cambridge Biomedical Campus. Our group is interested in why patients with chronic liver disease develop liver cancer (hoarelab.uk). This is an exciting opportunity to join an MRC-funded 3-year project, based on previous findings from the group (Brunner et al, Nature, 2019; Ng et al, Nature, 2021) and will further define how acquired somatic mutations of key metabolism genes impact on cell survival, liver cancer development and systemic metabolic dysfunction. We are seeking to hire a motivated post-doctoral Research Associate with a background in epigenetics, cell biology, or cancer research to join the team. The successful candidate will join a pioneering research project investigating functional mechanisms and downstream consequences of recurrent somatic mutagenesis in chronic liver disease, in particular focusing on epigenetic...

A full or part-time working opportunity is available for a Postdoctoral Scientist to join the Mahata laboratory at the Division of Immunology, Department of Pathology, University of Cambridge, in a collaborative research project. The University of Cambridge is a world leader in biological research. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to Cambridge from all over the world, creating a lively international community to exchange ideas to discover and innovate. You will join a pioneering research programme to investigate the underlying principles of immune cell-mediated steroid biosynthesis in regulating cancer immunity. The research area offers an excellent opportunity to create a new dimension in cancer immunology, allowing you to develop your unique research niche and academic independence. You will thrive in a highly collaborative and supportive research environment. You should have a PhD, or due to...

Applications are invited for this new clinical academic post to be held within the Autism Research Centre (ARC) at the University of Cambridge, within the Department of Psychiatry. The ARC's mission is to understand the causes of autism and to establish which interventions are helpful and for whom. We welcome applications from postdoctoral scientists who are eligible for a Consultant post in the NHS as this post is for 3 days per week working in the Child and Adolescent Autism Clinical Pathway in the North East London Foundation Trust (NELFT), with 2 days per week undertaking research in the ARC. Funding for this role comes from a donation from NELFT to the University. The successful applicants will be expected to take the lead on writing grant applications to funders such as NIHR to fund the projects costs of their research and to extend their own salary beyond the first 5 years. It would be an advantage if candidates have an outstanding research record in autism...

The Department of Paediatrics is seeking a Clinical Research Associate with interests in cancer genomics. The Clinical Research Associate will be part of the Department of Paediatrics with close links to paediatric haematology and oncology and the Genomics Laboratory Hub. They will join an enthusiastic and collaborative group studying the clinical utility of whole genome sequencing of childhood neoplasms. They will have an honorary contract with Cambridge University hospitals and will contribute clinically as well as conducting research. The post is funded for 2 years in the first instance. The post-holder will get exposure and training in clinical cancer genomics, including discussion of data, contribution to MDTs, feedback to patients, whilst contributing to the delivery of the service. There will be a variety of opportunities for research with the main deliverable being a study of clinical utility. Applicants must be medically qualified, have (or be eligible for) full...

The Pharmacokinetics/Bioanalytics (PK/B) Core Facility based in the CRUK Cambridge Institute offers a diverse analytical service to the research groups for the quantification of small molecules in support of a wide range of pre-clinical and clinical based projects. The Research Assistant role will involve the development, validation and execution of quantitative LC-MS/MS methods for small molecules in a wide variety of biological matrices. We are looking for an experienced, motivated and focused individual willing to learn new laboratory skills. The role holder will be expected to focus on developing and validating bioanalytical assays according to the relevant regulatory guidelines, and apply these methods to routine analysis of samples from pre-clinical and clinical studies. In addition, you will assist as required in general laboratory administrative, housekeeping and maintenance duties. General duties involve the analysis of samples using quantitative LC-MS/MS...