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02 Feb, 2023
Full time
Postdoctoral Scholar Position in Digestive Diseases Taché Lab 2022-2023
University of California, Los Angeles Los Angeles, CA, USA
POSITION DESCRIPTION The Brain-Gut Interaction Laboratory, CURE/Digestive Disease Research Center in the Division of Digestive Diseases at the University of California Los Angeles is seeking a full time Post-Doctoral Research Fellow for a project funded through the NIH OT2 SPARC (Stimulating Peripheral Activity to Relieve Conditions) initiative. The research project is focused on 3D imaging and computational quantitation of extrinsic and intrinsic innervation and nerve-mast/glial cell spatial relationship in the human colonic mucosa for neuromodulation in patients with irritable bowel syndrome (IBS). The Post-Doctoral Research Fellow will apply cutting-edge technologies and softwares related to confocal microscopy, imaging, 3D reconstruction, tracing and segmentation by using Imaris and Neurolucida to quantitate extrinsic and intrinsic innervation of IBS phenotypes in relation with MCs-EGCs spatial configuration in 3D structure of the sigmoid colonic biopsies in healthy...
02 Feb, 2023
Full time
Postdoctoral Scholar Position in Digestive Diseases Jacobs Lab 2022-23
University of California, Los Angeles Los Angeles, CA, USA
POSITION DESCRIPTION The Jacobs Laboratory in the UCLA Microbiome Center and the Division of Digestive Diseases, Department of Medicine at the David Geffen School of Medicine at UCLA, is seeking applicants for a post-doctoral position in microbiome science. The laboratory studies the role of intestinal microbes in inflammatory bowel disease (IBD) and other gastrointestinal diseases using a combination of multi-omics analysis of human cohorts to define microbiome-phenotype associations and in vivo models to elucidate underlying biological mechanisms. The candidate will investigate the hypothesis that IBD-associated genetic variants disrupt pathways that regulate the intestinal microbiota, thereby creating a microbial pre-disease susceptibility state. This will be pursued through the use of gene edited and conditional knockout mice to model the effect of IBD-associated genetic variants on the microbiome. The relevance of these microbial shifts will be further investigated...
02 Feb, 2023
Full time
Postdoctoral Scholar Position in Digestive Diseases 2022-2023
University of California, Los Angeles Los Angeles, CA, USA
POSITION DESCRIPTION The Center for Neurobiology of Stress and Resilience in the Division of Digestive Diseases at the University of California Los Angeles is seeking a full time Post-Doctoral Research Fellow for a U54-funded project studying sex-related differences in the brain-gut-microbiome interactions related to visceral pain. This project is focused on the sex-specific effect of gut microbial metabolites, and estrogen levels on ascending arousal pathways originating in distinct brainstem nuclei to change the activity and connectivity of brain networks involved in symptom generation in irritable bowel syndrome. As a part of an multidisciplinary research team the fellow will apply advanced computational, neuroimaging, biostatistical, and bioinformatics approaches to assess the interaction between various levels of biological data (e.g., microbiota, metabolites, sex hormones, multimodal brain and brainstem imaging data), clinical variables (symptom severity,...
02 Feb, 2023
Full time
Postdoctoral Scholar Position in Digestive Diseases 2022-2023
University of California, Los Angeles Los Angeles, CA, USA
POSITION DESCRIPTION The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA and the VA Greater Los Angeles Health System are seeking applicants for a full-time Postdoctoral Scholar position in the Stress-Neurogastroenterology laboratory. The candidate will participate in projects involving anatomical profiling of neuronal circuits in the pelvic organs-autonomic nervous system, using tracing, immunohistochemistry, image reconstruction and molecular biology assays. The position will offer the candidate an excellent opportunity to advance their career path and to obtain training in new methodological approaches. A PhD, DVM or MD is required with some experience and interest in neuroanatomical and immunohistochemical studies and in microscopy and imaging processing. Knowledge and experiences preferred in autonomic nervous system, microscopy, and image processing. The candidate must be enthusiastic, have strong written...
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