18 jobs found in solna

Do you want to contribute to top quality medical research? The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet in Stockhom conducts research and teaching in infection biology, immunology, cell biology and cancer. Our keywords are interdisciplinary, clinically based basic research and national and international cooperation. Division The research group of Dr Claudia Kutter seeks a Postdoc (either computational or computational/experimental) in the field of functional genomics and RNA biology. The Kutter lab has a track record in deciphering molecular mechanism by which RNAs (i.e. long noncoding, transfer and small RNA) regulate genes and genome structure in mammalian somatic tissue and in the germline (Geng et al. Genome Research 2022, Søndergaard et al. Gut, 2022, Gao et al. Genome Research 2022, Atanasoai et al. bioRxiv 2021). As a Postdoc in the Kutter lab you will be part of a multidisciplinary and collaborative research team...

Do you want to contribute to top quality medical research? The Division of Infectious Diseases performs research and education in close collaboration with the Karolinska University Hospital. The research teams address a wide range of infectious diseases using clinical, epidemiological and experimental approaches. The Sundling Research Team focuses on understanding the immune response to different pathogens with the aim to find biomarkers to better distinguish them on a molecular level. We are now recruiting a research assistant for a short-term project focusing on experimental immunology to investigate how the immune system is affected by infection with Mycobacterium tuberculosis (Mtb). The studies involve both experimental lab work and bioinformatic analysis. The studies are based on well characterized cohorts recruited in Sweden and via collaborators. The research group is based at the new research laboratories at BioClinicum on the Karolinska University Hospital site...

Do you want to contribute to top quality medical research? At the Division of Rheumatology, Department of Medicine, Solna, we conduct research on diseases affecting the musculoskeletal system, including inflammatory and non-inflammatory diseases. The Division of Rheumatology offers good opportunities for clinical research on large and unique patient groups from the clinic along with biomedical and experimental animal research. Your mission Your duties will be to assist lab management within our research group and work in research projects within immune-mediated diseases e.g., systemic lupus erythematosus (SLE), lupus nephritis (LN) and rheumatoid arthritis. It will involve design of experiments in wet lab, performing experiments, preparation of samples for high throughput analyses, statistical evaluation and bioinformatics analysis. Preparation of research articles for publication will be a part of mission in collaboration with other group members. Your profile...

Do you want to contribute to top quality medical research? Cardiovascular disease (CVD) is, the leading cause of mortality and a major cause of morbidity in Europe, affecting the lives of over 49 million people and costing €200 billion to the EU economy. The dysregulated chronic inflammation behind atherosclerotic CVD and its cardiovascular consequences are largely caused by a failure in the resolution of inflammation. The Unit of Integrative Metabolomics and the Translational Cardiology group and are seeking 1-2 postdoctoral fellows to work in the framework of the recently funded HORIZON project “CARE-IN-HEALTH (2023-2027). The ambition of the CARE-IN-HEALTH project is to take the chronic inflammation concept to the next level:  Resolution-health.  The project goal is to enable a paradigm shift in staying healthy via promotion of the resolution of inflammation. The main aim is to identify the resolution of the chronic lipid-driven/-regulated vascular...

Do you want to contribute to top quality medical research? Cardiovascular disease (CVD) is, the leading cause of mortality and a major cause of morbidity in Europe, affecting the lives of over 49 million people and costing €200 billion to the EU economy. The dysregulated chronic inflammation behind atherosclerotic CVD and its cardiovascular consequences are largely caused by a failure in the resolution of inflammation. The Unit of Integrative Metabolomics and the Translational Cardiology group and are seeking 1-2 postdoctoral fellows to work in the framework of the recently funded HORIZON project “CARE-IN-HEALTH (2023-2027). The ambition of the CARE-IN-HEALTH project is to take the chronic inflammation concept to the next level:  Resolution-health.  The project goal is to enable a paradigm shift in staying healthy via promotion of the resolution of inflammation. The main aim is to identify the resolution of the chronic lipid-driven/-regulated vascular...

Do you want to contribute to top quality medical research? We invite applications for a postdoctoral position in the laboratory of Professor Ernest Arenas http://ernestarenaslab.org/. The position will be placed in the Division of Molecular Neurobiology, a cluster of 8 research groups forming a dynamic and collaborative research environment within the MBB department, at the Karolinska Institute. Our laboratory is located in the Karolinska Institute, one of the world's leading medical universities and home of the Nobel Prize in Medicine or Physiology. Karolinska Institutet conducts cutting edge medical research and holds the largest range of medical research and education in Sweden. Positions will be placed in Biomedicum, one of the largest and most modern research buildings in Northern Europe. Our lab offers an inclusive, interactive, multidisciplinary and international research work environment, where you can enjoy science and develop your career....

Do you want to contribute to top quality medical research? The Department of Neuroscience has the mission to conduct ground-breaking research on the nervous system. Our 35 research groups study the function of the nervous system in health and disease, at the molecular, cellular, and network level. We now intend to strengthen our research profile in sensory neurobiology, broadening our scientific portfolio to the study of developmental aspects as well as cellular and network organization of specific sensory systems using animal models. This will also provide an ideal complement to clinical research on sensory function currently carried out at Karolinska Institutet. We are in the new Biomedicum building, which hosts a multidisciplinary environment with five basic science departments and top-level core facilities. Description of the subject area The sensory nervous system is a part of the nervous system responsible for detecting and processing sensory information. The...

Do you want to contribute to top quality medical research? The Department of Oncology-Pathology is searching for a post-doctoral fellow to work with Dr Ola Larsson and co-workers to study the role of mRNA translation in cancer. Dysregulated mRNA translation is emerging as a central facet in cancer progression that is incompletely understood. The Larsson group is seeking the upstream signals as well as the downstream effectors underlying transcript-selective alterations of translation in cancer. The overall goal is to understand how mRNA translation can be targeted in future anti-cancer therapy. Division The Larsson lab focuses on understanding the role of mRNA translation in several cancer types; and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA...

Do you want to contribute to top quality medical research? Applications are invited for postdoctoral positions in the group of Joanna Rorbach at the Division of Molecular Metabolism, Karolinska Institutet, Stockholm. The positions can be offered as postdoctoral scholarship or temporary employment. Division of Molecular Metabolism The Division of Molecular Metabolism (http://ki.se/en/mbb/research-divisionof-molecular-metabolism, http://ki.se/en/mbb), is located in Biomedicum, Solna campus of Karolinska Institutet. The research at the division aims at understanding the regulation of mitochondrial function and the role of mitochondrial dysfunction in disease. The current research encompasses biochemical and genetic studies of patients with inherited diseases as well as basic scientific approaches to understand the regulation of mtDNA expression and other aspects of mitochondrial metabolism. The Division of Molecular Metabolism offers an outstanding research...

Join us in developing education of the highest quality The applicant will be recruited as KIRI postdoc fellow, KI Research Incubator (KIRI) is created by the Committee for Research KI for a dynamic environment to strengthen innovative research collaborations with a focus on interdisciplinary breakthroughs. Therefore, this applicant will work in two labs of KIRI fellows: Qiaolin Deng, Associate professor, Dept. Physiology and Pharmacology, Georgios Sotiriou, Associate professor, Dept. Microbiology, Tumor and Cell Biology. The research project for this position focuses on development of cell-type specific nanoparticles to prevent fetal programming by dysfunctional placentas. Fetal programming also known as developmental origins of health and disease, proposes that early exposure to suboptimal conditions in utero translates into adverse health outcomes in later life. In particular, this project focusses on the roles of gene regulation of placenta function exposed to glucose...

Do you want to contribute to top quality medical research? A postdoctoral position within the exciting field of gene regulatory networks in cancer is immediately available in the laboratory of Professor Jussi Taipale who heads research groups at Karolinska Institutet, University of Cambridge and University of Helsinki. This position is based at the Department of Medical Biochemistry and Biophysics, Karolinska Institutet. Research group The laboratory focuses on the study of transcriptional control of cell growth, using functional genomics and systems biology and as such the research groups consist of both experimental biologists and computer scientists. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, using this information to identify regulatory elements that control cell growth during normal development or in cancer and validation of identified elements using cultured cells and...

Do you want to contribute to top quality medical research? The Department of Oncology-Pathology is searching for a postdoctoral fellow to work with Dr. Rolny and co-workers to study gene expression programs governing tumor-associate macrophage (TAM) phenotypes during tumor development. The Department of Oncology-Pathology conducts basic, translational and clinical research and educational activities related to cancer. The research group has longstanding experience in the field of the tumor microenvironment field, and is a member of the Swedish Tumor Microenvironment Program and the Breast Cancer Theme Center. More details about the groups can be found here. Your mission The Rolny lab focuses on mechanism that governs TAMs immunosuppressive and pro-metastatic functions. Over the years, Rolny and co-workers, have provided evidence that reprograming of TAM pro-tumor phenotype into an anti-tumor phenotype is a valid anti-cancer strategy. We have...

Do you want to contribute to improving human health? The “Genome Integrity” group at the Karolinska Institutet - SciLifeLab, led by  Prof. Jiri Bartek  has one postdoc vacancy. Part of our research focuses on various mechanistic aspects of ribosome biogenesis and protein translation in cancer biology. Using a combination of wet-lab techniques and bioinformatics we aim to discover markers and druggable targets that can be exploited for personalized therapy. A major aspect of our work is functional characterization of proteins and cellular signaling pathways involved in genome stability maintenance, ribosome biogenesis, and protein synthesis. See also recent publications from the research group including Zisi  et al ., 2022, Neuro-Oncol.; Kanellis  et al ., 2021, Science Adv.; Espinoza  et al , 2020, Cell Death Diff. For further information visit https://ki.se/en/mbb/jiri-bartek-group Division and Research Group Our group...

Do you want to contribute to top quality medical research? At the Division of Rheumatology at the Department of Medicine, Solna research is conducted on diseases affecting the musculoskeletal system, inflammatory as well as non-inflammatory. The Division of Rheumatology offers good opportunities to both clinical research on large and unique patient groups from the clinic along with biomedical and experimental animal research. The position is full-time for 6 months with the possibility of extension. Your mission You will work with research projects in SLE. Duties include independent work with coordination of projects and translational studies within SLE. Your profile We are looking for you who have pursued innovative research and have a deep understanding of autoimmune diseases. You should be able to understand and speak Swedish at a basic level, and you should be fluent in English, both spoken and written. Great emphasis is placed on personal qualities....

Do you want to contribute to top quality medical research? The Department of Oncology-Pathology is searching for a post-doctoral fellow to work with Dr Ola Larsson and co-workers to study the role of mRNA translation in cancer. Dysregulated mRNA translation is emerging as a central facet in cancer progression that is incompletely understood. The Larsson group is seeking the upstream signals as well as the downstream effectors underlying transcript-selective alterations of translation in cancer. The overall goal is to understand how mRNA translation can be targeted in future anti-cancer therapy. Division The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA...

Do you want to contribute to the development of new immunotherapies for cancer? In our lab we focus on the tumor microenvironment to find targets for immunotherapy for cancer. We have found that targeting using specific antibodies for Tumor Associated Macrophages (TAM) can be used for treatment of cancer (PNAS; 2020, 15;117 and Cell Rep; 2016, 100;2000). We are now developing this treatment for human application and are also investigating other possibilities for modifying the functions of TAMs for treatment purposes. Division Prof. Mikael Karlssons group is at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet, in Solna (Biomedicum). The department conducts research and teaching in immunology, infectious biology, cell biology and cancer. Our keywords are interdisciplinary, clinically based basic research and national and international cooperation. Duties The postdoc will work to understand the interplay between TAMs and other...

Do you want to contribute to top quality medical research? We are seeking a highly motivated and ambitious individual from universities around the world to join the research team (Division of Cardiology) of Assistant Professor Zhichao Zhou and Professor John Pernow as a Postdoctoral Fellow to mechanistically understand novel disease mechanisms underlying diabetes-associated cardiovascular complications and identify new therapeutic targets to treat diabetic patients suffering from cardiovascular complications. We are located in a modern research hub called BioClinicum at Karolinska Institutet in Solna. You will be working in an international and interdisciplinary research environment, where collaborative efforts are encouraged. We always aim for an open and welcoming environment. Together with other research groups, the Cardiovascular Theme offers state-of-the art cell culture, molecular biology, functional analysis and microscopy facilities. This position will be supported...

Do you want to contribute to improving human health? Division The newly started Ketzef laboratory, closely affiliated to the Silberberg laboratory at the Department of Neuroscience, has an open position for a postdoctoral fellow. We are searching for talented and enthusiastic postdocs interested in studying the neural networks of the basal ganglia underlying sensorimotor functions using electrophysiological, optical, and molecular methods. Duties The successful candidate should show a high level of responsibility and independency, be able to collaborate with others in a team, and possess good English communication skills. Applicants should have a strong neuroscience background with documented experience in electrophysiology. Experience in surgery, animal behavior, computer programming, and manuscript writing, are highly advantageous. The project will involve  in vivo  patch-clamp recordings, optogenetics, and imaging in the mouse basal ganglia....