126 Faculty - Science - Biochemistry and Molecular Biology jobs

Ref Number B02-04529 Professional Expertise Research and Research Support Department School of Life & Medical Sciences (B02) Location London Working Pattern Full time Salary £38,308- £46,155 Contract Type Fixed-term Working Type On site (> 80% of working time) Available For Secondment No Closing Date 14-Feb-2023 About us The UCL Great Ormond Street Institute of Child Health (GOS ICH) The mission of the UCL GOS Institute of Child Health is to improve the health and well-being of children, and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their...

The Department of Molecular and Cellular Physiology is seeking an experimental research associate (Life Science Research Professional 2) to join the Huttenhain Laboratory to study how signaling receptors, specifically G protein-coupled receptors, decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. The ideal candidate will join the team in April 2023 or shortly after. Lab overview : The communication between cells and their environment depends on a finely tuned decoding of extracellular cues into an array of intracellular signaling cascades that drive a cellular response. These signals are integrated through highly dynamic and context specific signaling networks that collectively define the phenotypic output. Given the complexity and dynamic state of signaling networks, the current understanding of their constituents and how they are spatiotemporally regulated as a result of a specific input is...

We are looking for a highly motivated and dynamic postdoc for a 2-year position to commence 1 May 2023. The position concerns structure-function studies of the protein Ca2+/calmodulin (CaM)-dependent protein kinase 2 (CaMKII) – an important regulator of learning and memory in the mammalian brain. Information about the research group and work place can be found at the lab (Wellendorph lab) and department (www.drug.ku.dk) websites: Our research Our lab is devoted to understanding brain mechanisms involving the inhibitory neurotransmitter GABA (γ-aminobutyric acid) and its metabolite GHB (γ-hydroxybutyric acid) via their actions on their respective targets, including CaMKIIa. We use biochemical and pharmacological analyses in cells, tissues and whole organisms to elucidate the role of GHB and GABA targets in brain dysfunction. More recently we are also building knowledge in biophysics and structural biology to gain further mechanistic...

Cornell University embraces diversity and seeks candidates who will contribute to a climate that supports students, faculty and staff of all identities and backgrounds. We strongly encourage individuals from underrepresented and/or marginalized identities to apply. The College of Agriculture and Life Sciences at Cornell University embraces diversity and seeks candidates who will contribute to a climate that supports students, faculty, and staff of all identities and backgrounds. We strongly encourage individuals from underrepresented and/or marginalized identities to apply. The College of Agriculture and Life Sciences (CALS) is a pioneer of purpose-driven science and home to Cornell University’s second largest population of students, faculty and staff. We work across disciplines to tackle the challenges of our time through world-renowned research, education and outreach. The questions we probe and the answers we seek focus on three overlapping concerns: natural and...

Duff Medical Bldg. Full time JR0000037437 Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at McGill University), do not apply through this Career Site. Login to your McGill Workday account and apply to this posting using the Find Jobs report (type Find Jobs in the search bar). Position Summary: The successful candidate will join the newly established Krock laboratory that focuses on peripheral neuroimmune regulation of pain. Duties will include performing immunofluorescence staining experiments, cell culture experiments, microscopy, image analysis, solution making and lab set. More information about the lab is available at: https://www.mcgill.ca/dentistry/emerson-krock EDUCATION/EXPERIENCE Minimum requirement: Two years of undergraduate studies in neuroscience, cell and molecular biology,...

Work Arrangement:    On-Site Requisition Number:  228425 Regular or Temporary:  Regular Location:   Durham, NC, US, 27710 Personnel Area:  MEDICAL CENTER Date:   Feb 2, 2023 School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic...

Work Arrangement: Requisition Number:   206890 Regular or Temporary:   Regular Location:  Durham, NC, US, 27710 Personnel Area:  MEDICAL CENTER Date:  Feb 1, 2023 School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise...

Date:  12-Jan-2023 Location:  YONG LOO LIN SCH OF MEDICINE, Kent Ridge Campus, SG Company:  National University of Singapore Job Description The National University of Singapore invites applications for Research Assistant in the Laboratory of Molecular RNA Virology and Antiviral Strategies (MARVAS) which is hosted in the Department of Microbiology and Immunology and Infectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore. MARVAS specialises in translational antiviral research developments for human enteroviruses, mosquito-borne viruses (Zika, dengue and chikungunya viruses) and SARS CoV-2. You will have the opportunity to be familiar with molecular virology as well as high content screening technologies for antiviral drug discovery and translational antiviral strategies development. Appointments will be made on a one-year contract basis in the first instance, with the...

The Joseph Research Group is searching for postdoctoral or more senior candidates interested in computer simulation studies of intracellular spatiotemporal organization, biomolecular self-assembly, and soft condensed matter. The successful candidate will develop computer simulation approaches to understand compartmentalisation inside cells (e.g., formation of biomolecular condensates) and to leverage these findings for bioengineering applications. Candidates completing (i.e, with a confirmed defense/viva date) or holding a PhD in chemical engineering, chemistry, physics, bioengineering, or a closely related field, with a strong interest in biological systems are particularly encouraged to apply. We seek candidates with expertise in some of the following areas: molecular dynamics, Monte Carlo simulations, statistical mechanics, computer programming (e.g., C++, Python), polymer theory, molecular modeling (e.g., of proteins and nucleic acids), coarse-grain and polymer model...

A postdoctoral or more senior researcher opportunity is available immediately in the laboratory of Alexei Korennykh in the Department of Molecular Biology at Princeton University. We invite candidates with relevant PhD degrees to work in the fields of human cell biology and structural biology. Our research explores molecular and cellular mechanisms of immune receptors, which recognize "dark matter RNA" (non-coding RNAs) and shape autoimmune disorders and cancers.  Some of our core methods include tissue culture, cell biology, CRISPR knockout generation, various flavors of RNA-seq, RNA biochemistry, RNA biology, X-ray crystallography and Cryo-EM. High-resolution cryo-EM work is conducted at the recently built Cryo-EM center at Princeton. Our publications: https://pubmed.ncbi.nlm.nih.gov/?term=korennykh&sort=date&size=50 https://scholar.princeton.edu/korennykhlab/home Interested applicants should apply online at :...

Do you want to contribute to top quality medical research? The Department of Medical Epidemiology and Biostatistics (MEB) is among the largest departments of epidemiology in Europe with special focus on increasing our knowledge of the aetiology of different diseases. Our department consists of researchers, doctoral students, biostatisticians, data collectors and database administrators as well as administrative personnel, in total some 250 staff. The department is situated at campus Solna. Further information can be found at ki.se/meb Your mission The advent of high-throughput technologies has produced an avalanche of omics data and revolutionized medical research. Our research aims at developing and applying computational and statistical methodologies for analyses of multi-omics data from complex human diseases. The successful postdoctoral candidate will collaborate closely with our team members and external collaborators to analyze different omics-data for...

The laboratory of Prof. David Savage is seeking a research assistant to join an interdisciplinary team researching the links between obesity/ adipose tissue dysfunction and metabolic disease. The group has longstanding interests in rare human inherited disorders of adipose tissue, widely known as lipodystrophies. Remarkably, these diseases are strongly associated with almost identical metabolic disorders as those associated with obesity. Our lab studies humans, as well as using a range of model organisms and cell-based approaches to advance understanding of the mechanistic basis for these associations. The position is funded by the Wellcome Trust and will enable the successful applicant to join an international network using innovative approaches to tackle major challenges in human health. In this position, you will: - keep detailed and accurate records - play a leading role in laboratory management duties such as ordering, stock checks and organising lab inventories. - work...

The Department of Ecology and Evolutionary Biology and Department of Molecular Biology invites applications for a postdoctoral research associate or more senior research position to work with Professor Jessica Metcalf and Professor Mohamed Donia. The successful candidate will work on the ecology and evolution of acquiring bacterial symbionts. The recent discovery of many long-lasting symbiotic relationships between intracellular bacteria and host species scattered across the tree of life has excitingly extended our understanding of cross-species interactions. Yet, we still lack basic theory as to when and why such relationships emerge. Using a combination of computational analysis of existing gene sequences and mathematical models rooted in evolutionary ecology and mechanistic features of host/bacterial interactions, we aim to characterize settings under which such associations are expected to evolve Candidates are required to have a Ph.D. in quantitative ecology, molecular...

The Department of Molecular Biology at Princeton University currently has research positions available at the postdoctoral and more senior research levels in the areas of biochemistry, biophysics, cell biology, structural biology, microbiology, developmental biology, virology, genetics and cancer biology. Initial term is for one year with the possibility of reappointment based on satisfactory performance and continued funding. Interested applicants must apply online at https://www.princeton.edu/acad-positions/position/26721 and submit a cover letter, curriculum vitae, contact information for three references and a brief statement of research interests. These positions are subject to the University's background check policy. Essential Qualifications:  Candidates must have a Ph.D. or M.D. degree in a related field

The Department of Chemistry seeks to hire a Postdoctoral or more senior researcher for an appointment with Chemistry and Molecular Biology.  The candidate will work at the interface of two highly interactive groups, with strengths in physics, chemistry, and biology. (The successful applicant will be appointed through either the Chemistry Department or the Molecularly Biology Department, with a formal affiliation to the second department.) The research will consist of assembling, testing, and further developing a novel scanning probe microscope with ultrahigh spatial resolution (~nm) and single-molecule chemical species discrimination within a single biological cell at liquid helium temperature. Applicants should have experience with one or more of the following: scanning-probe microscopy, AFM-IR, ultrafast optics, nonlinear spectroscopy, experimental quantum control, nanoscale materials science, and/or molecular biology. Essential Qualifications: Candidates must hold...

Optimal development of the immune system requires defined environmental input in a spatiotemporally regulated manner. This fundamental process begins in utero in parallel to organogenesis. Numerous epidemiological data suggested that maternal environmental exposure during pregnancy, particularly infection, can shape the offspring's immunity in the long term. During this critical window, the mother also undergoes dramatic immunological changes to nurture and adapt to the semi-allograph fetus. The LIMmunity (Lab of Infant and Maternal Immunity) seeks to establish a mechanistic understanding of how maternal infection impacts offspring's long-term tissue immunity, and reciprocally, how maternal immunity adapt to physiological changes during pregnancy and lactation. Two fully-funded postdoctoral or more senior research positions are available in the LIMmunity to study fundamental maternal-offspring immune crosstalk. The opportunities are ideal for a highly motivated scholar with a...

Each of us harbor biological timers in our bodies known as the circadian clock. These clocks drive physiological processes and behaviors in coordination with the day-night cycle. Recent work has provided evidence that the circadian clock regulates immune functions in coordination with the day-night cycle. However, the underlying mechanisms by which the circadian clock drives rhythms in immunity are ill-defined.  The Brooks lab seeks to mechanistically determine circadian clock regulation of innate immune functions at the intestinal epithelial barrier. Forming the first line of defense, the intestinal epithelium must acquire nutrients from the diet while maintaining harmony with a vast consortium of microorganisms known collectively as the microbiota. Endemic to the epithelium are specialized epithelial and immune cell types that produce antimicrobial proteins, bolster the epithelial barrier, and coordinate immune responses. These fundamental functions of innate immunity are...

A postdoctoral or more senior research position is available in the Jimah Lab to study the mechanism of membrane fission processes, including endocytosis, in human cells. Projects include investigating the structural basis of proteins involved in membrane fission by single-particle cryo-EM structure determination, as well as investigating these proteins in vivo by cryo-electron tomography / cryo-correlative light and electron microscopy (cryo-ET / cryo-CLEM) enabled by cryo-FIB-SEM (focused ion beam/scanning electron microscopy). Investigations into the mechanism of membrane fission processes will utilize a multidisciplinary approach comprising biochemistry, biophysics, and cell biology to complement our primary tools from structural biology. The postdoctoral scholar will have access to cutting-edge cryo-EM equipment at the Imaging & Analysis Center and other instrumentation in various core facilities at Princeton University. The position is open and has a negotiable start...

A postdoctoral or more senior research position is available in the Jimah Lab to study organelle biogenesis, endocytosis, and other membrane remodeling processes in malaria and related parasites. Projects include single-particle cryo-EM structure determination of Plasmodium falciparum and Toxoplasma gondii proteins, and the structural biology of parasite proteins in their cellular context by cryo-electron tomography / cryo-correlative light and electron microscopy (cryo-ET / cryo-CLEM) enabled by cryo-FIB-SEM (focused ion beam/scanning electron microscopy). The postdoctoral scholar will have access to cutting-edge cryo-EM equipment at the Imaging & Analysis Center and access to other relevant instrumentation in various core facilities at Princeton University. The position is open  and has a negotiable start date. Although the initial appointment is for one-year, it is expected to be renewed contingent on satisfactory performance. This position will be within the...

Ref Number B02-04519 Professional Expertise Research and Research Support Department School of Life & Medical Sciences (B02) Location London Working Pattern Full time Salary £38,308- £46,155 Contract Type Permanent Working Type On site (> 80% of working time) Available For Secondment No Closing Date 12-Feb-2023 About us This is an exciting opportunity to join the group of Franca Fraternali, Professor in Integrative Computational Biology in the Department of Structural and Molecular Biology (https://www.ucl.ac.uk/biosciences/structural-and-molecular-biology) and Director of the ISMB. The Fraternali lab focuses on different aspects and methods in Structural Bioinformatics and Computational Biology/Biophysics, aiming at understanding at a molecular level the nature of the interactions occurring in the cell. The group uses and develops bioinformatics methods to analyse available data on protein structures and...